Chronic wet cough: Protracted bronchitis, chronic suppurative lung disease and bronchiectasis

Pediatric Pulmonology
A B ChangM L Everard

Abstract

The role of persistent and recurrent bacterial infection of the conducting airways (endobronchial infection) in the causation of chronic respiratory symptoms, particularly chronic wet cough, has received very little attention over recent decades other than in the context of cystic fibrosis (CF). This is probably related (at least in part) to the (a) reduction in non-CF bronchiectasis in affluent countries and, (b) intense focus on asthma. In addition failure to characterize endobronchial infections has led to under-recognition and lack of research. The following article describes our current perspective of inter-related endobronchial infections causing chronic wet cough; persistent bacterial bronchitis (PBB), chronic suppurative lung disease (CSLD) and bronchiectasis. In all three conditions, impaired muco-ciliary clearance seems to be the common risk factor that provides organisms the opportunity to colonize the lower airway. Respiratory infections in early childhood would appear to be the most common initiating event but other conditions (e.g., tracheobronchomalacia, neuromuscular disease) increases the risk of bacterial colonization. Clinically these conditions overlap and the eventual diagnosis is evident only with further ...Continue Reading

References

Jan 1, 1992·Journal of Applied Physiology·J K RainsP D Paré
Nov 1, 1991·Acta Radiologica·K YoungA Kolbenstvedt
Jan 1, 1987·Journal of Computer Assisted Tomography·P M Silverman, J D Godwin
Jan 1, 1984·British Journal of Diseases of the Chest·P D Phelan
Jun 1, 1982·Journal of Computer Assisted Tomography·D P NaidichS S Siegelman
Jan 1, 1994·Scandinavian Journal of Infectious Diseases·P Gottfarb, A Brauner
Jan 1, 1994·Archives of Disease in Childhood·S McKenzie
Feb 1, 1994·Archives of Disease in Childhood·W H Nikolaizik, J O Warner
Jun 1, 1993·Family Practice·C S CornfordL Ridsdale
Jan 1, 1993·Scandinavian Journal of Infectious Diseases·J DarelidB E Malmvall
Jan 1, 1993·European Journal of Applied Physiology and Occupational Physiology·S AhmaidiC Préfaut
Jan 1, 1993·Respiratory Medicine·J KorpásM Vrabec
Nov 16, 1996·Lancet·L SimonsJ McCallum
Feb 1, 1997·The European Respiratory Journal·M Seear, D Wensley
Aug 1, 1997·Respiratory Medicine·O SäynäjäkangasS L Kivelä
Jan 1, 1997·Pediatric Pulmonology. Supplement·J JustA Grimfeld
Mar 11, 1998·The European Respiratory Journal·T KeistinenS L Kivelä
Apr 8, 1999·Archives of Disease in Childhood·A O FaniranA J Woolcock
Jul 16, 1999·Pediatric Pulmonology·A B Chang
Feb 24, 2000·Pediatric Pulmonology·R SingletonC Lewis
Mar 29, 2000·Archives of Disease in Childhood·R S CaneS A McKenzie
Jun 1, 2000·Indian Journal of Pediatrics·G R Sethi, V Batra
Dec 22, 2000·Archives of Disease in Childhood·R S Cane, S A McKenzie
Dec 22, 2000·Archives of Disease in Childhood·H E ElphickM L Everard
Jul 31, 2001·Pediatric Pulmonology·G B KarakocS G Kendirli
Nov 9, 2001·Radiologic Clinics of North America·D M Hansell
May 10, 2002·Pediatric Pulmonology·Charles W Callahan, Gregory J Redding
Jul 12, 2002·The Journal of Allergy and Clinical Immunology·Benjamin Gaston
Jul 12, 2002·The Journal of Allergy and Clinical Immunology·Jocelyne JustAlain Grimfeld
Jul 12, 2002·Pediatric Pulmonology·Fazilet KarakoçElif Dağli
Aug 15, 2002·The Medical Journal of Australia·Anne B ChangUNKNOWN Working Group on Indigenous Paediatric Respiratory Health
Oct 3, 2002·The European Respiratory Journal·J A Wedzicha, J F Muir
Dec 18, 2002·Health & Social Care in the Community·Richard HardingRichard Moorhead
Apr 24, 2003·Pediatrics International : Official Journal of the Japan Pediatric Society·Figen AkalInElif Dagli
May 15, 2003·Pediatric Pulmonology·A B ChangP J Torzillo
Jul 15, 2003·Respirology : Official Journal of the Asian Pacific Society of Respirology·Yasushi HashimotoShoji Kudoh

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Citations

Aug 16, 2011·Lung·Miles Weinberger
Jan 29, 2013·Annals of Biomedical Engineering·Vinayak SwarnkarRina Triasih
Feb 12, 2009·Journal of Paediatrics and Child Health·Helen L PetskyAnne B Chang
Sep 22, 2010·Journal of Paediatrics and Child Health·Kerry-Ann F O'Grady, Anne B Chang
Nov 3, 2010·Journal of Paediatrics and Child Health·Haya Al Subie, Dominic A Fitzgerald
Apr 9, 2009·American Journal of Respiratory and Critical Care Medicine·Andrew Bush
Apr 12, 2013·Cough·Michael D Shields, Surendran Thavagnanam
Aug 28, 2012·Journal of Asthma and Allergy·Nevin W WilsonVanessa Wong
Feb 11, 2014·Archivos de bronconeumología·Adelaida LamasLuis Máiz
Sep 7, 2013·Early Human Development·Ahmad KantarOliviero Sacco
Feb 14, 2014·Archives of Disease in Childhood·Vikas GoyalAnne B Chang
Mar 7, 2014·Annals of the American Thoracic Society·Christopher J van der GastLucas R Hoffman
Jun 13, 2014·Wiener klinische Wochenschrift·Angela ZacharasiewiczUNKNOWN Austrian Society of Pediatrics and The Austrian Society of Pneumology
Jun 25, 2014·Paediatric Respiratory Reviews·A B ChangG J Redding
Jul 20, 2012·Expert Opinion on Emerging Drugs·Anne B ChangLucas R Hoffman
Mar 5, 2015·Expert Opinion on Emerging Drugs·Anne B ChangLucas R Hoffman
Feb 4, 2016·Pediatric Pulmonology·Vikas GoyalAnne B Chang
Oct 13, 2015·Lung·Ahmad Kantar
Jan 18, 2014·Chest·Danielle F WurzelAnne B Chang
May 31, 2013·Paediatric Respiratory Reviews·Michael D Shields, Gary M Doherty
Jun 26, 2012·Paediatric Respiratory Reviews·Sam Mehr
Aug 6, 2014·Chest·Bruce K RubinMarkus O Henke
Oct 30, 2010·Immunology and Allergy Clinics of North America·Matti Korppi
Dec 22, 2010·Paediatric Respiratory Reviews·Jayesh M Bhatt, Alan R Smyth
Feb 23, 2010·Otolaryngologic Clinics of North America·Anne B Chang, Robert G Berkowitz
Apr 23, 2010·Annals of Allergy, Asthma & Immunology : Official Publication of the American College of Allergy, Asthma, & Immunology·Bradley E Chipps
Dec 8, 2009·Pediatric Clinics of North America·Anne B ChangP J Torzillo
Dec 8, 2009·Pediatric Clinics of North America·Gregory J Redding, Catherine A Byrnes
Jan 13, 2009·Pediatric Clinics of North America·Gregory J Redding
Jan 13, 2009·Pediatric Clinics of North America·Anne B Chang
Feb 27, 2013·Journal of Paediatrics and Child Health·Matthew J MoreyAnne B Chang
Aug 11, 2011·Pediatric Pulmonology·Nitin KapurAnne B Chang

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