Sep 1, 1977

Chronobiological characteristics of the cytological indicators of the islands of Langerhans in mice

Problemy e̊ndokrinologii
R S Nikodimova

Abstract

This experimental work was conducted on 40 sexually mature albino mice; with the aid of cytometry and cytochemistry the 24-hour rhythm of functional activity of beta-cells of the pancreas was shown. An enlargement of the nuclei and nucleoli of beta-cells, an accumulation of specific fuchsinophilic and zinc-containing granules was noted at night (10 p.m.--6 a.m.); this pointed to the high functional activity of the insular cells at this time. During the day (10 a.m.--6 p.m.) the volume of the nuclei and nucleoli proved to decrease, and the specific granularity of beta-cells became less pronounced. Circadian rhythmicity of the insulin production by beta-cells was also indicated by the changed count of the insulin-containing blood erythrocytes.

  • References
  • Citations

References

  • We're still populating references for this paper, please check back later.
  • References
  • Citations

Citations

  • This paper may not have been cited yet.

Mentioned in this Paper

Benign Tumor of Pancreas
Cell Nucleus
Novolin
Staining and Labeling
Pancreatic Diseases
Entire Pancreas
Cytometry
Cytochemistry
Erythrocytes
Islets of Langerhans

About this Paper

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Synthetic Genetic Array Analysis

Synthetic genetic arrays allow the systematic examination of genetic interactions. Here is the latest research focusing on synthetic genetic arrays and their analyses.

Autism: Motor Learning

A common feature of autism spectrum disorder (ASD) is the impairment of motor control and learning, consistent with perturbation in cerebellar function. Find the latest research on ASD and motor learning here.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

Sexual Dimorphism in Neurodegeneration

There exist sex differences in neurodevelopmental and neurodegenerative disorders. For instance, multiple sclerosis is more common in women, whereas Parkinson’s disease is more common in men. Here is the latest research on sexual dimorphism in neurodegeneration

Protein Localization in Disease & Therapy

Localization of proteins is critical for ensuring the correct location for physiological functioning. If an error occurs, diseases such as cardiovascular, neurodegenerative disorders and cancers can present. Therapies are being explored to target this mislocalization. Here is the latest research on protein localization in disease and therapy.

Genetic Screens in Bacteria

Genetic screens can provide important information on gene function as well as the molecular events that underlie a biological process or pathway. Here is the latest research on genetic screens in bacteria.

Head And Neck Squamous Cell Carcinoma

Squamous cell carcinomas account for >90% of all tumors in the head and neck region. Head and neck squamous cell carcinoma incidence has increased dramatically recently with little improvement in patient outcomes. Here is the latest research on this aggressive malignancy.

Artificial Intelligence in Cardiac Imaging

Artificial intelligence (ai) techniques are increasingly applied to cardiovascular (cv) medicine in cardiac imaging analysis. Here is the latest research.