PMID: 7033668Jan 1, 1982Paper

Chuchuhuasha - a drug used in folk medicine in the Amazonian and Andean areas. A chemical study of Maytenus laevis

Journal of Ethnopharmacology
J G GonzalezG B Marini-Bettolò

Abstract

In the high Amazonian basin a plant named chuchuasha, (or chuchuaso) is used in traditional medicine for several purposes in the form of an alcoholic extract. This plant, a Maytenus species, most probably Maytenus laevis, grows in the subandean region of the Amazonian basin (Peru, Ecuador, Colombia). Antitumor and anti-inflammatory properties were recently attributed to the extracts of the root bark of the plant. The composition of the extract of M. laevis from the Putumayo area of Colombia was studied in order to establish the active principle responsible for these activities. The presence of phenoldienones (tingenone, 22-hydroxytingenone), a catechin (4'-methyl-(-)-epigallocatechin) and proanthocyanidins (Ouratea-proanthocyanidins A and B) was established. The biological activities of these compounds confirm the properties of the extracts of the plant claimed by traditional medicine.

Citations

Jul 19, 2008·Breast Cancer Research and Treatment·Thangaiyan Rabi, Anupam Bishayee
Feb 19, 2008·Archives of Pharmacal Research·Sérgio Faloni de AndradeRivaldo Niero
Sep 2, 2004·Chemical & Pharmaceutical Bulletin·Osamu ShirotaHideji Itokawa
Jun 10, 2004·Chemical & Pharmaceutical Bulletin·Osamu ShirotaHideji Itokawa
Jul 17, 2007·Journal of Ethnopharmacology·Sérgio Faloni de AndradeRivaldo Niero
Feb 26, 2008·Toxicology in Vitro : an International Journal Published in Association with BIBRA·Patricia Marçal da CostaCláudia Pessoa
Nov 5, 2016·Revista Da Sociedade Brasileira De Medicina Tropical·Dionatas Ulises de Oliveira MeneguettiValdir Alves Facundo
Apr 27, 2000·Bioorganic & Medicinal Chemistry Letters·H ChávezD García-Grávalos
Jun 6, 2002·Revista Do Instituto De Medicina Tropical De São Paulo·Lucienir Pains DuarteArtur da Silveira Pinto
Nov 13, 2010·Chemistry & Biodiversity·Gaoyan Lian, Biao Yu
Jun 5, 2013·Journal of Basic and Clinical Physiology and Pharmacology·Ismail O IsholaMicah C Chijioke
Aug 12, 2005·Molecular Cancer Therapeutics·Chin-Chung WuYang-Chang Wu
Jan 23, 1999·Journal of Natural Products·S PiacenteC Pizza
Aug 8, 2021·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Yuan-Yuan HuangJing-Quan Yuan
Nov 26, 2010·Journal of Natural Products·Sandra M Oramas-RoyoAna Estévez-Braun
Jan 29, 2000·Journal of Natural Products·A G GonzálezA G Ravelo
Sep 10, 1999·Journal of Natural Products·A G GonzálezL Moujir
Dec 1, 2004·Journal of Natural Products·Hiroyuki NakagawaSharif Uddin Ahmed

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.