Chyle leakage patterns and management after oncologic esophagectomy: A retrospective cohort study

Thoracic Cancer
Dohun KimYoung Mog Shim

Abstract

This study aims to evaluate the incidence and characteristics of chyle leakage after curative oncologic esophagectomy, and the effectiveness of thoracic duct ligation. This is a retrospective cohort study using the medical records of 1514 patients who underwent curative esophagectomy for esophageal cancer between September 1994 and December 2010. Patients whose pleural fluid analysis corresponded to chyle were included, and drainage patterns by different management groups were examined with multilevel models. The chyle leakage patterns during the time before and after duct ligation were also evaluated, adjusting for demographics, clinical characteristics, and treatment. The prevalence of chyle leakage after esophagectomy was 3.8%. The three management groups were as follows: (i) conservative-controlled only with conservative management; (ii) surgical I-duct ligation during the esophagectomy; and (iii) surgical II-duct ligation after the esophagectomy. Pattern analysis determined that drainage of the conservative group was ∼400 mL/day (maximum on postoperative days [POD] = 9.2); drainage of surgical II was ∼1000 mL/day (maximum on POD = 18.1). On average, thoracic duct ligation was performed 18.7 days after the esophagectomy, an...Continue Reading

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Citations

Mar 5, 2021·Surgical Endoscopy·Aaron R DezubeJon O Wee
Mar 17, 2021·Diseases of the Esophagus : Official Journal of the International Society for Diseases of the Esophagus·Robert PowerJohn V Reynolds

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