Cigarette smoking in male patients with chronic schizophrenia in a Chinese population: prevalence and relationship to clinical phenotypes.

PloS One
Xiang Yang ZhangThomas R Kosten

Abstract

The high prevalence of smoking in schizophrenia of European background may be related to smoking's reducing clinical symptoms and medication side effects. Because smoking prevalence and its associations with clinical phenotypes are less well characterized in Chinese than European patients with schizophrenia, we assessed these smoking behaviors using clinician-administered questionnaires and the Fagerstrom Test for Nicotine Dependence (FTND) in 776 Chinese male schizophrenia and 560 control subjects. Patients also were rated on the Positive and Negative Symptom Scale (PANSS), the Simpson and Angus Extrapyramidal Symptom Rating Scale (SAES), and the Abnormal Involuntary Movement Scale (AIMS). We found that the schizophrenia patients had a higher lifetime incidence of smoking (79% vs 63%), were more likely to be heavy smokers (61% vs 31%), and had lower smoking cessation rates (4% vs 9%) (all p<0.0001) than controls. Among the schizophrenia patients smoking prevalence increased with age, with the largest difference from controls in the age cohort of 55-75 years: 75% vs 46% (p<0.0001). Among the schizophrenia smokers 73% started to smoke before the onset of their illness by an average of 7.6 years. The patients with schizophrenia w...Continue Reading

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Citations

Jul 24, 2012·Schizophrenia Research·Pedro F DerozaAlexandra I Zugno
Mar 29, 2016·Neuroscience Bulletin·Hui-Mei AnXiang-Yang Zhang
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Dec 1, 2018·Translational Psychiatry·Huimei AnXiang Yang Zhang
Sep 5, 2019·Journal of Geriatric Psychiatry and Neurology·Junjun LiuXiangrong Zhang
Dec 29, 2016·Journal of Neural Transmission·Sergej NadalinAlena Buretić-Tomljanović
Jun 11, 2019·General Psychiatry·Yan LiYu-Tao Xiang
Nov 5, 2016·Journal of Clinical Psychopharmacology·Qiongzhen LiXiang Yang Zhang
Apr 26, 2019·Frontiers in Psychology·Su-Jiao LiuWan-Sen Yan
Sep 15, 2016·Comprehensive Psychiatry·Sergej NadalinVesna Šendula Jengić

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Methods Mentioned

BETA
pharmacotherapy

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