PMID: 42421Oct 1, 1979

Cimetidine in the prevention of the pulmonary acid aspiration (Mendelson's) syndrome

British Journal of Anaesthesia
G DobbJ G Williams


Cimetidine 200 mg was given i.v. 1 h before induction of anaesthesia to 20 patients about to undergo emergency surgery. There was an increase in pH of gastric aspirate in all patients (P less than 0.001) and in 80% pH was greater than 2.5 units at the time of induction of anaesthesia. The pH of gastric aspirate continued to increase after induction of anaesthesia and was greater than 4 units in all patients at the time of tracheal extubation and in the early recovery period.


Sep 1, 1982·Klinische Wochenschrift·G FeifelH Eissner
Mar 1, 1986·Canadian Anaesthetists' Society Journal·A J Cunningham, P Barry
May 1, 1983·Canadian Anaesthetists' Society Journal·J G Williams
Jan 1, 1984·Pharmacology & Therapeutics·R E Pounder
Mar 29, 1980·Lancet·A Gilston
Sep 17, 1981·The New England Journal of Medicine
May 1, 1982·Anaesthesia and Intensive Care·J WrobelJ M Saunders
Jan 1, 1996·The Journal of International Medical Research·H Tanioka, K Kaga
May 1, 1983·Anaesthesia and Intensive Care·J G Brock-UtneJ Gjessing
May 1, 1984·Drug Intelligence & Clinical Pharmacy·S F Kowalsky

Related Concepts

Gastric Juice
Gastroesophageal Reflux Disease
General Anesthesia
Inspiration Function
Hydrogen-Ion Concentration
Operative Surgical Procedures

Trending Feeds


Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Synapse Loss as Therapeutic Target in MS

As we age, the number of synapses present in the human brain starts to decline, but in neurodegenerative diseases this occurs at an accelerated rate. In MS, it has been shown that there is a reduction in synaptic density, which presents a potential target for treatment. Here is the latest research on synapse loss as a therapeutic target in MS.

Artificial Intelligence in Cardiac Imaging

Artificial intelligence (ai) techniques are increasingly applied to cardiovascular (cv) medicine in cardiac imaging analysis. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

Social Learning

Social learning involves learning new behaviors through observation, imitation and modeling. Follow this feed to stay up to date on the latest research.

Cell Atlas of the Human Eye

Constructing a cell atlas of the human eye will require transcriptomic and histologic analysis over the lifespan. This understanding will aid in the study of development and disease. Find the latest research pertaining to the Cell Atlas of the Human Eye here.

Single Cell Chromatin Profiling

Techniques like ATAC-seq and CUT&Tag have the potential to allow single cell profiling of chromatin accessibility, histones, and TFs. This will provide novel insight into cellular heterogeneity and cell states. Discover the latest research on single cell chromatin profiling here.

Genetic Screens in iPSC-derived Brain Cells

Genetic screening is a critical tool that can be employed to define and understand gene function and interaction. This feed focuses on genetic screens conducted using induced pluripotent stem cell (iPSC)-derived brain cells.