Cinnamon in glycaemic control: Systematic review and meta analysis

Clinical Nutrition : Official Journal of the European Society of Parenteral and Enteral Nutrition
Rajadurai AkilenNicola Robinson

Abstract

Cinnamon seems to be highly bioactive, appearing to mimic the effect of insulin through increased glucose uptake in adipocytes and skeletal muscles. This systematic review and Meta analysis examined the effect of cinnamon on glycaemic control in patients with Type 2 Diabetes mellitus. A systematic literature search was conducted from the earliest possible date through to 01 August 2011. Search terms included free text terms, MeSH and Medline medical index terms such as: "cinnamon", "cinnamomum", "cinnamomum cassia", "cinnamomum zeylanicum", "type 2 diabetes mellitus". Each was crossed with the term "diabetes mellitus". In addition, references of key articles were hand searched. A total of 6 clinical trials met the strict inclusion criteria and considered a total of 435 patients; follow up between 40 days-4 months, doses ranging from 1 g to 6 g per day. Meta-analysis of RCTs showed a significant decrease in mean HbA1c [0.09%; 95% CI was 0.04-0.14] and mean FPG [0.84 mmol/l; 95% CI was 0.66-1.02]. Use of cinnamon showed a beneficial effect on glycaemic control (both HbA1c and FPG) and the short term (<4 months) effects of the use of cinnamon on glycaemic control looks promising.

References

Sep 18, 1999·Archives of Pharmacal Research·C Y Jung, W Lee
Mar 22, 2000·Journal of Agricultural and Food Chemistry·C L BroadhurstR A Anderson
Jul 21, 2000·The Journal of Clinical Investigation·J E Pessin, A R Saltiel
Aug 17, 2001·Journal of the American College of Nutrition·K J Jarvill-TaylorD J Graves
Nov 25, 2003·Diabetes Care·Alam KhanRichard A Anderson
Jan 8, 2004·Journal of Agricultural and Food Chemistry·Richard A AndersonDonald J Graves
Dec 25, 2004·Diabetes Care·UNKNOWN American Diabetes Association
Feb 18, 2006·Diabetes Care·David Power
Mar 27, 2007·Pharmacotherapy·Antony Q PhamDavid Q Pham
Mar 30, 2007·Diabetes Care·Justin A AltschulerKevin M Curtis
Jun 15, 2007·Diabetes Care·Steve M BlevinsChristopher E Aston
Oct 3, 2007·Diabetes Care·William L BakerCraig I Coleman
Oct 11, 2007·Diabetes, Obesity & Metabolism·T P J Solomon, A K Blannin
Feb 1, 2008·The Proceedings of the Nutrition Society·Richard A Anderson
May 27, 2008·Journal of the International Society of Sports Nutrition·Tim N ZiegenfussRichard A Anderson
Jan 23, 2009·European Journal of Applied Physiology·Thomas P J Solomon, Andrew K Blannin
Jul 3, 2009·Journal of the American College of Nutrition·Anne-Marie RousselRichard A Anderson
Sep 8, 2009·Journal of the American Board of Family Medicine : JABFM·Paul Crawford

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Citations

Nov 10, 2013·Pakistan Journal of Biological Sciences : PJBS·Firas Sultan Azzeh
Feb 25, 2014·Pflügers Archiv : European journal of physiology·Julio Alvarez-CollazoJulio L Alvarez
Jul 20, 2012·Clinical Nutrition : Official Journal of the European Society of Parenteral and Enteral Nutrition·Nanne KleefstraHenk J G Bilo
Sep 22, 2016·Research in Pharmaceutical Sciences·Azadeh MesripourMahmoud Rafieian-Kopaie
Oct 30, 2016·Journal of the Academy of Nutrition and Dietetics·Rebecca B CostelloEdwina Wambogo
Jan 19, 2016·Phytomedicine : International Journal of Phytotherapy and Phytopharmacology·Arrigo F G Cicero, Alessandro Colletti
Feb 26, 2016·European Journal of Nutrition·Giuseppe GrossoAndrzej Pająk
Jan 7, 2015·Saudi Journal of Biological Sciences·Shaheena BanuShams Tabrez
Jan 5, 2018·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Paolo GovernaMarco Biagi
Apr 25, 2020·Animals : an Open Access Journal From MDPI·Jeremy J CottrellFrank R Dunshea
Jul 22, 2017·Frontiers in Pharmacology·Ajda Ota, Nataša P Ulrih
Sep 8, 2018·Biological Trace Element Research·Luísa L GonçalvesJosé A Brito
Apr 6, 2019·International Journal of Food Science·Nildem Kizilaslan, Nihal Zekiye Erdem
Jan 15, 2020·Pharmaceutical Medicine·Amanda BergaminAlison M Hill
Jan 21, 2020·Food Research International·Samad Ghaffari, Neda Roshanravan
Feb 28, 2021·Complementary Therapies in Medicine·Parivash Shekarchizadeh-EsfahaniCyrus Jalili
Aug 20, 2021·The American Journal of Medicine·Chayakrit KrittanawongSalim S Virani

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