Cinnamon oil: A possible alternative for contact lens disinfection

Contact Lens & Anterior Eye : the Journal of the British Contact Lens Association
Rasha H BassyouniEman Mostafa

Abstract

To investigate the antibacterial activity of cinnamon oil alone and in combination with a multipurpose contact lens disinfectant solution (MPS) as well as tobramycin against multi drμg resistant conjunctival bacteria both in planktonic and sessile forms. Minimum inhibitory concentrations (MIC) of tobramycin and cinnamon oil against 19 bacterial strains were investigated against planktonic and sessile cells by micro-dilution methods. Synergistic effects were determined by well diffusion and micro-dilution tissue culture plate methods for planktonic and sessile cells respectively. Time kill assay was performed to study the bactericidal effect of cinnamon oil in concentrations ranging from 5% to 0.312% combined with an MPS with respect to time. MICs of cinnamon oil against planktonic bacteria ranged from 0.04% to 1.25% versus 0.156% to 5% for sessile cells. Combination of cinnamon oil with tobramycin had a synergistic effect against most tested organisms. The MIC values of cinnamon oil in combination with tobramycin was significantly lower than cinnamon oil alone against biofilm production (P=0.004). Time kill assay revealed that combination of cinnamon oil and disinfectant successfully eradicated the tested microorganisms at all ...Continue Reading

References

Dec 1, 1996·Journal of the Royal Society of Medicine·F A Jones
Jul 23, 1998·Journal of Applied Microbiology·L McLaughlin-BorlaceJ K Dart
May 8, 2000·The Journal of Antimicrobial Chemotherapy·J MayG L French
Apr 3, 2004·Letters in Applied Microbiology·S StepanovićM Svabić-Vlahović
Oct 13, 2004·Phytotherapy Research : PTR·A SimićP D Marin
May 10, 2005·Ophthalmology·Antonio PinnaFrancesco Carta
Sep 15, 2009·Applied and Environmental Microbiology·Titik NuryastutiBastiaan P Krom
May 7, 2010·Ophthalmic & Physiological Optics : the Journal of the British College of Ophthalmic Opticians (Optometrists)·Maureen BoostPauline Cho
Jul 27, 2010·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Yuangang ZuNan Wu
Aug 20, 2010·Investigative Ophthalmology & Visual Science·Yvonne T WuFiona Stapleton
Sep 10, 2010·Case Reports in Medicine·Konstantinos T TsaousisPeriklis Tahiaos
Sep 29, 2011·Optometry and Vision Science : Official Publication of the American Academy of Optometry·Danielle M Robertson, H Dwight Cavanagh

❮ Previous
Next ❯

Related Concepts

Related Feeds

Biofilm & Infectious Disease

Biofilm formation is a key virulence factor for a wide range of microorganisms that cause chronic infections.Here is the latest research on biofilm and infectious diseases.

Aminoglycosides (ASM)

Aminoglycoside is a medicinal and bacteriologic category of traditional Gram-negative antibacterial medications that inhibit protein synthesis and contain as a portion of the molecule an amino-modified glycoside. Discover the latest research on aminoglycoside here.

Aminoglycosides

Aminoglycoside is a medicinal and bacteriologic category of traditional Gram-negative antibacterial medications that inhibit protein synthesis and contain as a portion of the molecule an amino-modified glycoside. Discover the latest research on aminoglycoside here.

Biofilms

Biofilms are adherent bacterial communities embedded in a polymer matrix and can cause persistent human infections that are highly resistant to antibiotics. Discover the latest research on Biofilms here.

Related Papers

Natural Product Communications
Lívia SlobodníkováDaniel Grancai
The Southeast Asian Journal of Tropical Medicine and Public Health
Sroisiri Thaweboon, Boonyanit Thaweboon
Microbial Drug Resistance : MDR : Mechanisms, Epidemiology, and Disease
María Elena Velazquez-MezaMiguel Angel Sánchez-Alemán
© 2022 Meta ULC. All rights reserved