Circadian Dysfunction and Obesity: Is Leptin the Missing Link?

Cell Metabolism
Charna Dibner, Frédéric Gachon

Abstract

While accumulating evidence suggests that circadian desynchrony is linked to obesity and metabolic syndrome, the underlining mechanism is still poorly understood. In this issue, Kettner et al. (2015) demonstrate that leptin resistance, induced by circadian clock deficiency or chronic jet lag, may represent this missing link.

References

Sep 7, 2005·Cell·Loning FuGerard Karsenty
Oct 3, 2009·Biochimica Et Biophysica Acta·Pablo B Martínez de MorentinMiguel López
Dec 30, 2014·Current Opinion in Cell Biology·Romain Volmer, David Ron

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Citations

Mar 2, 2016·International Journal of Molecular Sciences·Víctor MicóLidia Daimiel
May 12, 2018·The Proceedings of the Nutrition Society·Randy J Nelson, Souhad Chbeir
Nov 23, 2017·The New England Journal of Medicine·Anna M Diehl, Christopher Day
Sep 18, 2018·International Journal of Molecular Medicine·Qianwen MaBeibei Zhou
Dec 16, 2020·International Journal of Molecular Sciences·Maite Martínez-UñaMarta G Novelle
Jun 3, 2021·International Journal of Molecular Sciences·Benedetta RussoSimona Frontoni

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