Apr 9, 2005

Circadian effects of timed meals (and other rewards)

Methods in Enzymology
Alec J DavidsonMichael Menaker

Abstract

Mammals organize many of their activities around rhythmic events in their environments. Primary among these events is the daily light-dark cycle. However, for many animals, food availability is rhythmic or quasi-rhythmic and is therefore a potential synchronizing cue. While circadian rhythms in both behavior and physiological activity can be entrained in animals via meal-feeding schedules, the mechanism by which this occurs remains poorly understood. Similarities between the circadian effects of restricted feeding and the effects of chronic methamphetamine treatment may be indicative of a common mechanism. This article argues that reward (or the arousal that accompanies it) may be the final common pathway for such nonphotic circadian inputs.

Mentioned in this Paper

Mesocricetus auratus
Biochemical Pathway
Behavior, Animal
Oscillators, Biological
Periodicity
Neutropenia, Severe Congenital, X-Linked
Circadian Clocks
FOSB protein, human
PGAP3 gene
Methamphetamine Measurement

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