Circadian hemodynamic characteristics in hypertensive patients with primary aldosteronism

Journal of Hypertension
Hiroshi KusunokiFumiki Yoshihara

Abstract

The present study aimed to compare circadian hemodynamic characteristics in hypertensive patients with and without primary aldosteronism. Circadian hemodynamics, including 24-h brachial and central blood pressure (BP), SBP variability indices, central pulse wave velocity (PWV), augmentation index (AIx@75), cardiac index, and total vascular resistance (TVR), were evaluated using an oscillometric device, Mobil-O-Graph, in 60 patients with primary aldosteronism (63.4±13.3 years, 47% women) and 120 age-matched and sex-matched patients with essential hypertension. Office SBP, PWV, AIx@75, and BP variability indices were similar between groups; however, 24-h brachial (124 ± 14 vs 130 ± 11 mmHg) as well as central (112 ± 12 vs 120 ± 10 mmHg) SBP was higher (both P < 0.01), and the difference between 24-h brachial and central SBP (11 ± 5 vs 9 ± 3 mmHg, P < 0.05), an index of pressure amplification, was smaller in primary aldosteronism than in essential hypertension. In both groups, cardiac index decreased from daytime to night-time (both P < 0.01), but this decrease was smaller in primary aldosteronism (P < 0.05). During daytime, TVR in primary aldosteronism was higher than that in essential hypertension (P < 0.05), and the significant...Continue Reading

References

Feb 15, 1986·The American Journal of Cardiology·R B DevereuxN Reichek
Jul 1, 1995·Hypertension·D P VeermanG A van Montfrans
May 1, 1995·American Journal of Hypertension·F VeglioL Chiandussi
Feb 3, 1999·Journal of Human Hypertension·F VeglioL Chiandussi
Jul 24, 2002·Hypertension Research : Official Journal of the Japanese Society of Hypertension·Akira YamashinaYoshio Yamamoto
Apr 20, 2005·Journal of the American College of Cardiology·Paul MilliezJean-Jacques Mourad
Nov 18, 2005·The Journal of Clinical Endocrinology and Metabolism·Francesco FalloPaolo Mulatero
Sep 27, 2006·European Heart Journal·Stephane LaurentUNKNOWN European Network for Non-invasive Investigation of Large Arteries
May 6, 2009·Annals of Internal Medicine·Andrew S LeveyUNKNOWN CKD-EPI (Chronic Kidney Disease Epidemiology Collaboration)
Mar 4, 2010·European Heart Journal·Charalambos VlachopoulosChristodoulos Stefanadis
Mar 11, 2010·Blood Pressure Monitoring·Wolfgang WeiMarkus van der Giet
Mar 17, 2010·Lancet Neurology·Peter M RothwellUNKNOWN ASCOT-BPLA and MRC Trial Investigators
Mar 20, 2010·Journal of Human Hypertension·S WassertheurerD Magometschnigg
Apr 27, 2010·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·Masaru HorioSeiichi Matsuo
May 8, 2010·Journal of the American College of Cardiology·Andreas TomaschitzHarald Dobnig
Jul 8, 2010·Hypertension·Eamon Dolan, Eoin O'Brien
Jul 27, 2010·Blood Pressure Monitoring·Pascal M L Franssen, Ben P M Imholz
Aug 14, 2010·American Journal of Hypertension·Leonardo A SechiCristiana Catena
Jul 2, 2011·Journal of Hypertension·John J SimStephen F Derose
Aug 11, 2011·Endocrine Journal·Tetsuo NishikawaUNKNOWN Task Force Committee on Primary Aldosteronism, The Japan Endocrine Society
Jan 25, 2014·European Heart Journal·Carmel M McEnieryIan B Wilkinson

❮ Previous
Next ❯

Citations

Nov 21, 2019·Proceedings of the Institution of Mechanical Engineers. Part H, Journal of Engineering in Medicine·Theodore G PapaioannouDimitrios Tousoulis
May 24, 2021·BMC Cardiovascular Disorders·Prossie Merab IngabireUNKNOWN CREOLE Study Investigators

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.