Circadian modulation of osmoregulated firing in rat supraoptic nucleus neurones

Journal of Neuroendocrinology
Eric Trudel, Charles W Bourque

Abstract

The antidiuretic hormone vasopressin (VP) promotes water reabsorption from the kidney and levels of circulating VP are normally related linearly to plasma osmolality, aiming to maintain the latter close to a predetermined set point. Interestingly, VP levels rise also in the absence of an increase in osmolality during late sleep in various mammals, including rats and humans. This circadian rhythm is functionally important because the absence of a late night VP surge results in polyuria and disrupts sleep in humans. Previous work has indicated that the VP surge may be caused by facilitation of the central processes mediating the osmotic control of VP release, and the mechanism by which this occurs was recently studied in angled slices of rat hypothalamus that preserve intact network interactions between the suprachiasmatic nucleus (SCN; the biological clock), the organum vasculosum lamina terminalis (OVLT; the central osmosensory nucleus) and the supraoptic nucleus (SON; which contains VP-releasing neurohypophysial neurones). These studies confirmed that the electrical activity of SCN clock neurones is higher during the middle sleep period (MSP) than during the late sleep period (LSP). Moreover, they revealed that the excitation ...Continue Reading

References

Jul 1, 1976·Kidney International·G L RobertsonS Athar
Aug 1, 1975·The Journal of Clinical Endocrinology and Metabolism·C P GeorgeM Kuchel Orofo-Oftega
Apr 1, 1976·The Journal of Clinical Endocrinology and Metabolism·G L Robertson, S Athar
Mar 1, 1991·Endocrinology·J G VerbalisE M Stricker
Jan 1, 1989·Annual Review of Neuroscience·R S Zucker
Jul 15, 1988·Annals of Internal Medicine·C L Fraser, A I Arieff
Jul 1, 1971·The Journal of Physiology·J J DreifussK B Ruf
Dec 1, 1973·The Journal of Clinical Investigation·F L DunnG L Robertson
Jan 1, 1983·Progress in Brain Research·D J RamsayL C Keil
Sep 1, 1994·Frontiers in Neuroendocrinology·C W BourqueD Richard
Jul 31, 1993·BMJ : British Medical Journal·A I Arieff
Oct 27, 1998·Chronobiology International·R Y Moore, R Silver
Oct 27, 1998·Chronobiology International·J LeSauter, R Silver
Apr 10, 1999·Nature Neuroscience·E D HerzogG D Block
Apr 24, 1999·Trends in Neurosciences·P FossierG Baux
May 5, 2000·Experimental Physiology·M L Forsling
Oct 19, 2000·Journal of the American Geriatrics Society·M Miller
Feb 15, 2001·American Journal of Physiology. Regulatory, Integrative and Comparative Physiology·A TakamataT Morimoto
Apr 12, 2001·The Journal of Comparative Neurology·R K Leak, R Y Moore
Aug 4, 2001·Pflügers Archiv : European journal of physiology·Y EndoK Shiraki

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Citations

Feb 23, 2013·The Journal of Urology·Hiromitsu NegoroOsamu Ogawa
Apr 23, 2013·The Journal of Comparative Neurology·Melissa J S CheeEleftheria Maratos-Flier
Apr 15, 2014·Neurourology and Urodynamics·Joseph G Verbalis
Jan 12, 2019·The European Journal of Neuroscience·Jodi R PaulKaren L Gamble
Nov 20, 2018·Journal of Neuroendocrinology·Gareth Leng, John A Russell
Aug 17, 2018·Endocrine, Metabolic & Immune Disorders Drug Targets·Michele IovinoVincenzo Triggiani
Nov 1, 2013·American Journal of Physiology. Renal Physiology·B MahlerS Rittig
Sep 8, 2017·American Journal of Physiology. Renal Physiology·Lynnette R Montgomery, Charles H Hubscher
Jul 5, 2017·Frontiers in Endocrinology·Heather B Patisaul
Nov 14, 2017·Nature Reviews. Nephrology·Claire Gizowski, Charles W Bourque

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