PMID: 11316329Apr 24, 2001Paper

Circadian rhythm of melatonin, corticosterone and phagocytosis: effect of stress

Journal of Pineal Research
C BarrigaA B Rodríguez

Abstract

Melatonin has a functional connection with the immune system. Phagocyte function is altered by extirpation of the pineal gland, one source of melatonin, or by in vitro incubation of phagocytes with pharmacological concentrations of melatonin. Given that its synthesis by pinealocytes is under the control of the noradrenaline released by the sympathetic postganglionaric nerve endings, the present work was aimed at evaluating the circadian rhythm of melatonin, corticosterone, and phagocytosis in BALB/c mice in basal and stress situations. Peritoneal macrophages were used as phagocytes, latex beads as the particles to be ingested, and forced swimming to exhaustion as the stress situation. Radioimmunoassay was used to determine the animals' serum hormone levels. Samples were taken every 3 hr in the period from 04:00 to 22:00 hr, and every 30 min during the remaining period from 22:00 to 04:00 hr. Control mice presented a short-term melatonin peak at 23:30 hr, while the maximum inert-particle ingestion capacity of the peritoneal macrophages also occurred during the night but at 03:30 hr. The corticosterone levels in control mice presented a circadian rhythm with a day-time maximum peak (16:00 hr). Compared with the controls, the anim...Continue Reading

Citations

Jul 10, 2007·Pflügers Archiv : European journal of physiology·Ciprian SanduFlorian Lang
Mar 29, 2008·Pflügers Archiv : European journal of physiology·Krishna M BoiniFlorian Lang
May 23, 2002·Biological Psychiatry·Lucianne GroeninkBerend Olivier
Dec 1, 2009·International Immunology·Vitalij CernysiovIrute Girkontaite
Apr 17, 2013·Clinical and Experimental Pharmacology & Physiology·Chooi Yeng Lee
Jul 25, 2013·Chronobiology International·Gabriela LasteWolnei Caumo
May 7, 2013·American Journal of Otolaryngology·Vural FidanCemal Cingi
Oct 23, 2012·American Journal of Otolaryngology·Vural FidanCemal Cingi
Oct 2, 2012·General and Comparative Endocrinology·Kirsten Rosenmaj JacobsenKlas S P Abelson
Mar 30, 2004·Journal of Neuroscience Research·Melissa M HolmesGerd Kempermann
Sep 23, 2014·Psychopharmacology·Kevin J NormanKlaus A Miczek
Sep 13, 2013·Laboratory Animals·T L JensenL F Mikkelsen
Feb 25, 2009·Laboratory Animals·I H E KasanenT O Nevalainen
Apr 13, 2013·International Journal of Molecular Sciences·M Ángeles EstebanJosé Meseguer
Mar 24, 2018·Scientific Reports·Marcelo P MarinovicMirian A F Hayashi
Nov 18, 2017·Journal of the Royal Army Medical Corps·Seyyedeh Soghra MousaviS Parvin
Mar 28, 2008·American Journal of Physiology. Regulatory, Integrative and Comparative Physiology·Rexhep RexhepajFlorian Lang
Jun 15, 2019·Chronobiology International·David J Kennaway
Jun 25, 2019·The Journal of Laryngology and Otology·E SenturkM V Kiziltaş
Sep 21, 2019·PloS One·Stefanny Christie Monteiro TitonVania Regina Assis
May 13, 2020·The Journal of Immunology : Official Journal of the American Association of Immunologists·Lena ReiskeVolker Stefanski
Jun 20, 2008·Molecular and Cellular Biochemistry·Soledad SánchezCarmen Barriga
Dec 29, 2020·General and Comparative Endocrinology·Stefanny Christie Monteiro TitonRegina P Markus
Sep 7, 2017·Scientific Reports·Zahra JafariMajid H Mohajerani

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.