Circadian rhythmicity in emerging mood disorders: state or trait marker?

International Journal of Bipolar Disorders
Ashlee B GriersonJan Scott

Abstract

Circadian rhythm disturbances overlap with the symptoms of mood episodes and may trigger or prolong mood symptoms. There is limited research on the role of circadian disturbances in mood disorders in young people and/or first episode cases of unipolar and bipolar disorders. Actigraphy was undertaken for about 14 days in 63 post-pubertal individuals aged 13-25 years with a recent onset of a mood disorder meeting recognised diagnostic criteria. We examined associations between three easily interpretable markers of circadian rhythm activity (amplitude, acrophase and rhythmicity index) and demography and clinical characteristics. Then, circadian markers were compared between diagnostic groups, controlling for potential confounders. Longer duration of illness was correlated with reduced circadian rhythmicity and lower levels of activity over 24 h. A delay in the timing of maximum activity was associated with the level of manic but not depressive symptoms. The circadian rhythmicity index differentiated unipolar from bipolar cases, and in bipolar but not unipolar disorder, the rhythmicity was less robust in those with more severe manic or depressive symptoms. Less robust circadian rhythmicity, especially associated with increasing sym...Continue Reading

References

Nov 1, 1978·The British Journal of Psychiatry : the Journal of Mental Science·R C YoungD A Meyer
Jul 1, 1993·Journal of the American Academy of Child and Adolescent Psychiatry·M H TeicherK Pahlavan
Feb 1, 1960·Journal of Neurology, Neurosurgery, and Psychiatry·M HAMILTON
May 29, 2004·Journal of the American Academy of Child and Adolescent Psychiatry·Roseanne ArmitageKelly Lewis
Aug 4, 2005·Chronobiology International·Hader A MansourVishwajit L Nimgaonkar
Feb 15, 2008·Bipolar Disorders·Paola SalvatoreRoss J Baldessarini
Jul 2, 2009·Psychiatry and Clinical Neurosciences·Maria Paz HidalgoMárcia Lorena Fagundes Chaves
Jan 29, 2010·Journal of Psychosomatic Research·Seog Ju KimSeong-Jin Cho
Mar 9, 2010·Chronobiology International·Ana AdanVincenzo Natale
Jun 17, 2011·Bipolar Disorders·Philipp S RitterAndrea Pfennig
Apr 6, 2013·Biological Psychiatry·Colleen A McClung
Jun 19, 2013·European Psychiatry : the Journal of the Association of European Psychiatrists·R RobillardI B Hickie
Sep 18, 2013·Current Psychiatry Reports·Rébecca RobillardIan B Hickie
Feb 7, 2014·The Journal of Clinical Psychiatry·Robert GonzalezTrisha Suppes
May 6, 2014·The Medical Journal of Australia·Ian B HickieNicholas Glozier
Jun 9, 2014·European Psychiatry : the Journal of the Association of European Psychiatrists·C BoudebesseB Etain
Aug 20, 2014·International Journal of Obesity : Journal of the International Association for the Study of Obesity·T Arora, S Taheri
Sep 10, 2014·Journal of Psychiatry & Neuroscience : JPN·Rébecca RobillardIan B Hickie
Sep 13, 2014·The British Journal of Psychiatry : the Journal of Mental Science·Jan ScottIan B Hickie
Nov 29, 2014·Acta Psychiatrica Scandinavica·P A GeoffroyB Etain
Feb 7, 2015·Journal of Affective Disorders·Chun Il ParkSe Joo Kim
Mar 3, 2015·Expert Opinion on Therapeutic Targets·Frank BellivierJan Scott
Jun 24, 2015·Chronobiology International·Hannah R TranelJody L Clasey
Jul 30, 2015·Schizophrenia Research·Juliana CastroSergio Tufik
Sep 17, 2015·Chronobiology International·Sarah FaresRébecca Robillard

❮ Previous
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Citations

Mar 22, 2016·International Journal of Molecular Sciences·Sang Won Jeon, Yong-Ku Kim
Aug 16, 2016·Sleep Medicine Reviews·Matias C A MeloVeralice M S de Bruin
Oct 8, 2016·Journal of Psychiatric Research·Thaíse Campos MondinRicardo Azevedo da Silva
Dec 21, 2017·BMC Psychiatry·Karoline Krane-GartiserJan Scott
Jun 6, 2018·Psychiatry and Clinical Neurosciences·Yoshikazu Takaesu
Nov 6, 2018·Chronobiology International·Jamie E M ByrneGreg Murray
Oct 21, 2018·Behavior Genetics·Susan T HarbisonTrudy F C Mackay
Mar 17, 2016·International Journal of Bipolar Disorders·Lauren E CudneyRoberto B Sassi
Apr 13, 2018·Translational Psychiatry·Oliver CarrGuy M Goodwin
May 18, 2019·British Journal of Sports Medicine·Alan CurrieClaudia L Reardon
Mar 7, 2017·Frontiers in Cellular Neuroscience·Yeni KimMaria C Marchetto
Dec 7, 2018·Chronobiology International·Amanda Neumann ReyesRicardo Azevedo da Silva
Mar 27, 2020·Annals of Behavioral Medicine : a Publication of the Society of Behavioral Medicine·Outi LinnarantaKai-Florian Storch
Feb 9, 2021·Journal of the American Academy of Child and Adolescent Psychiatry·Martijn ArnsAndrew N Coogan
Mar 11, 2021·Neuroscience and Biobehavioral Reviews·Joanne S CarpenterIan B Hickie

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