PMID: 6989263Mar 1, 1980Paper

Circadian sleep and feeding patterns in the rat: possible dependence on lipogenesis and lipolysis

The American Journal of Physiology
J Danguir, S Nicolaidis

Abstract

Sleep and feeding patterns were continuously recorded in rats under intravenous saline (control) and alternating insulin-epinephrine (experimental) infusions. The infusion of insulin (lipogenetic hormone) during the normally light period (0800-1600) replaced by epinephrine (lipolytic hormone) during the normally lipogenetic dark period (1600-0800) resulted in a complete inversion of the normal circadian distribution of sleep and feeding patterns and also of their correlation. Insulin infusion resulted in low blood glucose and glycerol levels whereas epinephrine increased these physiological parameters. Different control conditions showed that the fluctuations of sleep and feeding were dependent on the rate of utilization of the circulating metabolites at the cellular level. These results together with previous data suggest that the relation between sleep and feeding and their concomitant circadian fluctuation are possibly modulated by a common factor, namely the metabolic rate that is influenced by the lipogenesis/lipolysis rate.

References

Apr 1, 1979·Physiology & Behavior·J Danguir, S Nicolaidis
Apr 1, 1978·European Journal of Clinical Investigation·T Akerstedt, L Levi
Nov 1, 1978·Physiology & Behavior·J Danguir, S Nicolaidis
Jul 1, 1975·Physiology & Behavior·J M De Castro
Dec 1, 1971·The International Journal of Neuroscience·J R Mouret, P Bobillier
Jan 1, 1973·Pharmacology, Biochemistry, and Behavior·J PankseppP J Morgane
Sep 1, 1973·The Journal of Clinical Endocrinology and Metabolism·J F SassinE D Weitzman
Jan 1, 1974·Brain, Behavior and Evolution·H Zepelin, A Rechtschaffen
Jan 1, 1973·Hormone Research·T Jolin, A Montes
Jan 1, 1974·Pharmacology, Biochemistry, and Behavior·S NicolaidisA Pesez
May 1, 1974·Physiology & Behavior·D A Levitsky
Sep 1, 1974·The Journal of Clinical Investigation·R M BoyarL Hellman
Apr 1, 1972·Metabolism: Clinical and Experimental·J D Fernstrom, R J Wurtmen
Oct 1, 1968·Journal of Neurochemistry·A T Moir, D Eccleston
Mar 1, 1970·Metabolism: Clinical and Experimental·R W Fuller, E R Diller
Sep 1, 1970·Physiology & Behavior·C Timo-IariaT Leme da Rocha
Feb 1, 1954·Electroencephalography and Clinical Neurophysiology·M BONVALLETG HIEBEL
Nov 1, 1954·Electroencephalography and Clinical Neurophysiology·P DELLA HUGELIN

Citations

Dec 31, 2002·Physiological Reviews·L Arthur Campfield, Françoise J Smith
Feb 15, 2013·Toxicology and Industrial Health·Jaroslava NovákováFrantisek Nistiar

Related Concepts

Blood Glucose
Circadian Rhythms
Medihaler-Epi
Feeding Patterns
Glycerin
Novolin
Sleep, Slow-Wave

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Lipidomics & Rhinovirus Infection

Lipidomics can be used to examine the lipid species involved with pathogenic conditions, such as viral associated inflammation. Discovered the latest research on Lipidomics & Rhinovirus Infection.

Alzheimer's Disease: MS4A

Variants within the membrane-spanning 4-domains subfamily A (MS4A) gene cluster have recently been implicated in Alzheimer's disease in genome-wide association studies. Here is the latest research on Alzheimer's disease and MS4A.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Torsion Dystonia

Torsion dystonia is a movement disorder characterized by loss of control of voluntary movements appearing as sustained muscle contractions and/or abnormal postures. Here is the latest research.

Generating Insulin-Secreting Cells

Reprogramming cells or using induced pluripotent stem cells to generate insulin-secreting cells has significant therapeutic implications for diabetics. Here is the latest research on generation of insulin-secreting cells.

Central Pontine Myelinolysis

Central Pontine Myelinolysis is a neurologic disorder caused most frequently by rapid correction of hyponatremia and is characterized by demyelination that affects the central portion of the base of the pons. Here is the latest research on this disease.

Epigenome Editing

Epigenome editing is the directed modification of epigenetic marks on chromatin at specified loci. This tool has many applications in research as well as in the clinic. Find the latest research on epigenome editing here.