PMID: 9009166Jan 17, 1997Paper

Circadian-system alterations during cancer processes: a review

International Journal of Cancer. Journal International Du Cancer
M C Mormont, F Lévi

Abstract

Murine and human data have indicated that tumors and tumor-bearing hosts may exhibit nearly normal or markedly altered circadian rhythms. Amplitude damping, phase shifts, and/or period (tau) change, including appearance of ultradian rhythms (with tau < 20 hr) usually become more prominent at late stages of cancer development. The extent of rhythm alterations also varies according to tumor type, growth rate and level of differentiation. While "group chronotherapy," i.e., administration of the same chronomodulated schedule to cancer patients, has increased chemotherapy efficacy and/or tolerability, cancer patients' individual circadian rhythms now need to be explored on a large scale, in order to estimate the incidence of cancer-associated circadian-system alterations and to understand the underlying mechanisms. Correlations between such alterations and patient outcome must be established in order to specify the need for individualized chronomodulated delivery schedules and/or specific rhythm-oriented therapy, especially in patients with circadian-system disturbances.

Citations

Mar 22, 2002·The Lancet Oncology·F Lévi
Jan 25, 2002·European Journal of Cancer Care·S Ancoli-IsraelV Jones
Dec 8, 2005·Journal of the National Cancer Institute·Alison N SaulFirdaus S Dhabhar
Feb 25, 2006·Nature Reviews. Cancer·Michael H AntoniAnil K Sood
Sep 10, 2008·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Susan K LutgendorfDavid M Lubaroff
May 28, 2009·Cancer Research·Pasquale F InnominatoUNKNOWN Chronotherapy Group of the European Organization for Research and Treament of Cancer
Oct 19, 2010·Quality of Life Research : an International Journal of Quality of Life Aspects of Treatment, Care and Rehabilitation·Andrea BarsevickUNKNOWN GENEQOL Consortium
Dec 14, 2011·Immunotherapy·Paolo Lissoni, Franco Rovelli
Nov 18, 2004·Health Psychology : Official Journal of the Division of Health Psychology, American Psychological Association·Janine Giese-DavisDavid Spiegel
Jan 9, 2010·Annual Review of Pharmacology and Toxicology·Francis LéviJean Clairambault
Apr 11, 2014·International Review of Psychiatry·Jorge Luis SoteloCharles Nemeroff
Sep 21, 2010·International Journal of Hyperthermia : the Official Journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group·Kathleen M KokolusElizabeth A Repasky
Dec 14, 2007·Chronobiology International·Atanu Kumar PatiVivek Choudhary
Dec 9, 2015·International Journal of Clinical Pharmacy·Gagandeep KaurBandana Saini
Apr 3, 2013·Journal of Physiology, Paris·Diego A GolombekJuan J Chiesa
Oct 23, 2010·Biochimica Et Biophysica Acta·Mohammed ArifTapas K Kundu
Mar 24, 2010·Journal of Theoretical Biology·Jeremy D ScheffIoannis P Androulakis
Jan 26, 2010·Psychoneuroendocrinology·Emily A EismannSandra E Sephton
Jul 17, 2009·Medical Hypotheses·Balahan Makay, Erbil Unsal
Oct 16, 2007·Medical Hypotheses·Yong Zhu, Tongzhang Zheng
Aug 24, 2005·Critical Care Nursing Clinics of North America·Roberta Kaplow
Jul 22, 2014·International Journal of Cancer. Journal International Du Cancer·Sander A HuismanRon W F de Bruin
Dec 20, 2002·Cancer·Marie-Christine Mormont, Francis Levi
Apr 30, 2008·Molecular Carcinogenesis·Yueh-Min LinJan-Gowth Chang
Nov 11, 2006·International Journal of Cancer. Journal International Du Cancer·Yong ZhuTongzhang Zheng
Aug 7, 2012·International Journal of Cancer. Journal International Du Cancer·Matúš SotákJiří Pácha
May 9, 2013·European Journal of Clinical Investigation·Sebastian LarionHerbert L Bonkovsky
Nov 11, 2010·Journal of Pineal Research·Pedro LaxNicolás Cuenca
Jul 30, 2014·Pediatric Blood & Cancer·Valerie E RogersPamela S Hinds
May 18, 2004·Sleep Medicine Reviews·Kathryn LeeMarylin Dodd
Oct 8, 2014·Journal of Cancer Survivorship : Research and Practice·Eric L GarlandYoshio Nakamura

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