Circadian trafficking of calbindin-ir in fibers of SCN neurons.

Journal of Biological Rhythms
Joseph LesauterRae Silver

Abstract

Calbindin-D28K (CalB)-containing cells form a distinct cluster within the core of the hamster suprachiasmatic nucleus (SCN). These cells are directly retinorecipient but lack detectable rhythms in clock gene expression or electrical activity. In studies exploring SCN connectivity using double-label immunochemistry, we previously reported an absence of contacts among CalB fibers and vasopressin (VP) cells in animals sacrificed during the day. Here, we explored circadian variations in CalB-immunoreactivity (-ir) and re-examined the connections between CalB and other SCN cell types at zeitgeber times (ZT) 4 and 14. The results reveal a circadian rhythm of CalB-ir in fibers of SCN cells with high expression during the night and subjective night and low expression during the day and subjective day. This circadian difference is not seen in the other brain regions studied. Significantly more appositions were detected between CalB fibers and VP cells during the night than during the day, while circadian variation in numbers of contacts was not seen between CalB fibers and vasoactive intestinal polypeptide (VIP), cholecystokinin (CCK), or gastrin-releasing peptide (GRP) cells. There was no detectable variation in appositions from any pe...Continue Reading

References

Feb 1, 1996·Journal of Neurochemistry·L Winsky, J Kuźnicki
Apr 26, 1996·Neuroreport·R SilverJ LeSauter
Oct 1, 1996·Sleep·J D MillerR Y Moore
Mar 2, 2002·The Journal of Biological Chemistry·Tord BerggårdSara Linse
May 29, 2002·Neuroscience·J LeSauterR Silver
Dec 21, 2002·The European Journal of Neuroscience·Erin E Jobst, Charles N Allen
Mar 26, 2003·The European Journal of Neuroscience·Masayuki Ikeda, Charles N Allen
Aug 23, 2003·Journal of Biological Rhythms·Michael C AntleRae Silver
Jan 13, 2004·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Ilia N KaratsoreosRae Silver
Mar 12, 2004·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Lance J KriegsfeldRae Silver
Mar 11, 2005·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Michael C AntleRae Silver
Apr 6, 2005·Proceedings of the National Academy of Sciences of the United States of America·Hartmut SchmidtJens Eilers
Dec 2, 2005·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Timothy M BrownHugh D Piggins
Dec 13, 2005·Brain Research Reviews·L P Morin, C N Allen
Jan 24, 2006·Nature Reviews. Neuroscience·Mike Ludwig, Gareth Leng
Dec 2, 2006·Proceedings of the National Academy of Sciences of the United States of America·Sara J AtonErik D Herzog
Jan 19, 2007·Journal of Biological Rhythms·Michael C AntleRae Silver
Mar 10, 2007·The Journal of Physiology·Hartmut SchmidtJens Eilers
Sep 28, 2007·The European Journal of Neuroscience·Florence CayetanotFabienne Aujard
Jul 1, 2008·The European Journal of Neuroscience·Lance J KriegsfeldRae Silver
Dec 23, 2008·Cellular and Molecular Life Sciences : CMLS·B Schwaller
Feb 21, 2009·Journal of Computational Neuroscience·Hartmut Schmidt, Jens Eilers
Feb 13, 2010·The Journal of Comparative Neurology·Elise DrouyerRae Silver

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Citations

Feb 14, 2016·Experimental Eye Research·Ya-Nan GuChang-Jin Jeon
Apr 15, 2011·The European Journal of Neuroscience·Nicholas C FoleyRae Silver
Feb 24, 2015·Frontiers in Neuroendocrinology·Olivier BoslerAnne-Marie François-Bellan
Jun 23, 2016·Journal of Biological Rhythms·Robert Y Moore
Mar 10, 2018·The Journal of Comparative Neurology·Ruth MoronaAgustín González
Nov 8, 2018·The European Journal of Neuroscience·Vania Carmona-AlcocerJennifer A Evans
Apr 4, 2017·Neural Plasticity·Malgorzata Jasinska, Elzbieta Pyza
May 11, 2020·Current Biology : CB·Maria P FernandezOrie T Shafer

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