PMID: 9437516Jan 23, 1998Paper

Circadian variation of urinary type I collagen crosslinked C-telopeptide and free and peptide-bound forms of pyridinium crosslinks

Bone
H AoshimaT Inoue

Abstract

This study was performed to investigate the circadian variation of urinary CrossLaps (CTx), which was the type I collagen peptide released during bone matrix degradation, and peptide-bound and free forms of urinary pyridinium crosslinks. Urine was obtained during the 24 h of the study in seven separate collections as follows: from 23:00 h to the first void (FV) followed by FV at 11:00, 11:00-14:00, 14:00-17:00, 17:00-20:00, 20:00-23:00, and 23:00 h to FV the next morning. Total, free, and peptide-bound pyridinoline (Pyr) and deoxypyridinoline (Dpyr) excretion measured by high-performance liquid chromatography (HPLC) and CTx measured by enzyme-linked immunosorbent assay in nine premenopausal women aged 22-40 years and nine osteoporotic women aged 65-83 years was analyzed. Among three parameters of Pyr measured by HPLC, a significant day and night difference was found only in total Pyr (21.9% higher at night than during the day in premenopausal women and 24.0% in osteoporotic women, whereas no significant day and night variation was found in free and peptide-bound Pyr in either group. In contrast, total and peptide-bound Dpyr were significantly (37.9% and 66.9%) higher at night than those during the day in premenopausal women (38...Continue Reading

References

Sep 1, 1993·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·R EastellR G Russell
Apr 1, 1993·British Journal of Rheumatology·A M McLarenS P Robins

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Citations

Jul 17, 2008·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·P Szulc, P D Delmas
Feb 5, 2009·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·R CivitelliN Napoli
Aug 13, 2011·European Journal of Applied Physiology·Che-Fu LinRong-Sen Yang
Jul 19, 2011·Journal of Bone and Mineral Metabolism·Tadahiro IimuraAkira Yamaguchi
Jan 31, 2004·Bone·Dennis B HenriksenJens Juul Holst
Sep 1, 1999·Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research·P GarneroP D Delmas
Jan 15, 2004·American Journal of Veterinary Research·Bianca CarstanjenBenoit Remy
Sep 24, 1999·Current Opinion in Nephrology and Hypertension·S M Hart, R Eastell
Dec 8, 2000·Gynecological Endocrinology : the Official Journal of the International Society of Gynecological Endocrinology·P PeichlH Bröll
Apr 17, 2012·Clinical Biochemistry·S A Paul Chubb
Dec 1, 2009·Best Practice & Research. Clinical Rheumatology·Juliet Compston
Dec 6, 2006·Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research·Sanjin ZvonicJeffrey M Gimble
Dec 20, 2002·Endocrine Research·Masaaki TakahashiAkira Nagano
Mar 25, 2000·The American Journal of Clinical Nutrition·J GuillemantS Guillemant
Apr 6, 2006·The Journal of Bone and Joint Surgery. American Volume·A Robin Poole
Mar 7, 2021·International Journal of Environmental Research and Public Health·Alessandra AmatoSara Baldassano

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