PMID: 8613602Mar 15, 1996Paper

Circadian variations of onset of acute myocardial infarction and efficacy of thrombolytic therapy

Journal of the American College of Cardiology
T KonoA Fujiwara

Abstract

The present study investigated whether the onset of acute myocardial infarction and resistance to thrombolysis have similar circadian variations. Circadian variations of the onset of acute myocardial infarction and resistance to thrombolysis in the early morning have been reported. Some studies have also reported a secondary peak incidence in late evening; however, it is not known whether the resistance to thrombolysis has a similar circadian variation in these patients. Six hundred eight Japanese patients with an acute myocardial infarction were the subjects of the study. Two hundred forty-four of the 608 patients were treated with thrombolysis within 12 h of the onset of symptoms. One hundred thirteen patients received urokinase, and 131 patients received tissue-type plasminogen activator (t-PA) over 60 min. Patency of the infarct-related artery, the primary end point of the study, was evaluated at 60 min after the initiation of thrombolytic therapy, and Thrombolysis in Myocardial Infarction (TIMI) grade 0, 1 or 2 was defined as resistant to thrombolysis. The onset of acute myocardial infarction and resistance to thrombolysis showed circadian variations with early morning and late evening peaks (p<0.001 and p<0.05, respective...Continue Reading

References

Nov 1, 1975·Lancet·H T PedoeL McDonald
Apr 15, 1978·Lancet·M W Millar-CraigE B Raftery
Nov 21, 1985·The New England Journal of Medicine·J E MullerT Robertson
Aug 1, 1987·Circulation·M Fujita, D Franklin
Nov 1, 1987·The American Journal of Cardiology·A D BeamerL Goldman
Dec 31, 1987·The New England Journal of Medicine·H A Payne
Feb 1, 1985·International Journal of Cardiology·D R ThompsonP R Marchant
Sep 30, 1974·Clinica Chimica Acta; International Journal of Clinical Chemistry·M B Turton, T Deegan
Feb 1, 1994·British Heart Journal·T MasudaH Yasue

❮ Previous
Next ❯

Citations

Jun 1, 1997·The American Journal of Cardiology·M C CohenM A Mittleman
Dec 5, 1998·Thrombosis Research·R ManfrediniC Fersini
Jun 25, 2003·Journal of the American College of Cardiology·Jose P S HenriquesUNKNOWN Zwolle Myocardial Infarction Study Group
Sep 16, 2004·Clinical Evidence·Nicolas DanchinPhilip Urban
Jul 14, 2010·Circulation Journal : Official Journal of the Japanese Circulation Society·Takehiro TsukadaHideaki Yoshino
Sep 9, 2006·International Heart Journal·Ratko M LasicaZorana Vasiljevic
Apr 13, 2013·Clinical Medicine & Research·Rajan KanthShereif Rezkalla
Jul 12, 2001·Japanese Circulation Journal·K KinjoUNKNOWN Osaka Acute Coronary Insufficiency Study (OACIS) Group
Feb 4, 2010·Journal of Stroke and Cerebrovascular Diseases : the Official Journal of National Stroke Association·Denise H RhoneySteven R Levine
Jan 24, 2007·Journal of Cardiac Surgery·Ajay K DhadwalJoseph N Cunningham
Nov 8, 2012·Chronobiology International·Owen MogabgabEugene Braunwald
May 24, 2001·Progress in Cardiovascular Nursing·E J Bridges, S L Woods
Jun 25, 2003·Journal of the American College of Cardiology·Frederick A Spencer, Richard C Becker
Sep 18, 2016·Heart Failure Clinics·Roberto ManfrediniAbhishek J Deshmukh
Dec 10, 2017·Clinical Research in Cardiology : Official Journal of the German Cardiac Society·Stephane FournierUNKNOWN on behalf on the AMIS Plus Investigators
Aug 28, 2002·Circulation·Rajendra H MehtaUNKNOWN International Registry of Acute Aortic Dissection (IRAD) Investigators
Oct 9, 2018·Chronobiology International·Liang ZhangCuntao Yu
Dec 28, 2006·Clinical Cardiology·Troy LaBountyMelvyn Rubenfire
Aug 4, 2005·Chronobiology International·Roberto ManfrediniFabio Manfredini
Jan 13, 2006·Catheterization and Cardiovascular Interventions : Official Journal of the Society for Cardiac Angiography & Interventions·Abid R AssaliRan Kornowski
Apr 19, 2007·Annals of Medicine·Anne M Curtis, Garret A Fitzgerald
Oct 1, 2019·The Journal of Clinical Hypertension·Shougo MurakamiTatsuji Kono
Jun 6, 2013·Experimental and Therapeutic Medicine·Zhong-Ming WangDong-Ying Wang
Feb 22, 2021·Current Opinion in Pharmacology·Saurabh S Thosar, Steven A Shea

❮ Previous
Next ❯

Related Concepts

Related Feeds

Cardiology Journals

Discover the latest cardiology research in this collection of the top cardiology journals.