PMID: 7026646Oct 1, 1981Paper

Circannual variations in the B cell/T cell ratio in normal human peripheral blood

The Journal of Allergy and Clinical Immunology
A Bratescu, M Teodorescu

Abstract

In previous studies we have shown that B cells and subpopulations of T cells can be identified in blood smears with bacteria used as markers that bind spontaneously to lymphocytes. We have also identified Ig-bearing cells by using an Escherichia coli coated with anti-human Ig antibody. Here we determined the absolute values and the percentage of B cells and of other lymphocyte subpopulations in the peripheral blood of six normal donors every 2 mo for 1 yr. we found that the total leukocyte counts and the total number of lymphocytes remained unchanged throughout the year, whereas the percentage of B cells in the coldest month was at almost twice the level observed in summer. The percentage of cells that bind Arizona hinshawii ans Salmonella schottmülleri remained practically unchanged during the entire year. A variation was noted in the ratio between T1 and T2 cells, which also appears to be seasonally related. We speculate that hormonal factors, probably corticosteroids, are responsible for changes in the traffic of some lymphocyte subpopulations.

Citations

Jun 1, 1991·Aging : Clinical and Experimental Research·G P TrentiniM Criscuolo
Nov 1, 1995·Journal of Pineal Research·R J NelsonL J Kriegsfeld
Aug 21, 2014·Clinica Chimica Acta; International Journal of Clinical Chemistry·Chunmei HuangWei Cui
Mar 6, 2007·Journal of Immunological Methods·Karin Backteman, Jan Ernerudh
Mar 5, 2011·Journal of the European Academy of Dermatology and Venereology : JEADV·J KlodeJ Dissemond
Dec 25, 2003·International Journal of Dermatology·John G HancoxAlan B Fleischer
Oct 8, 1999·Chronobiology International·E Haus, M H Smolensky
Jun 19, 2013·Clinica Chimica Acta; International Journal of Clinical Chemistry·Francesca TosatoMario Plebani
Feb 1, 1985·Scandinavian Journal of Clinical and Laboratory Investigation·B Munch-PetersenM Faber
Dec 1, 1983·The American Journal of Anatomy·E HausL Sackett-Lundeen
Jun 2, 2009·The Journal of Bone and Joint Surgery. British Volume·A J HartJ J Powell
Jan 1, 1991·Annals of the New York Academy of Sciences·F LéviJ L Misset
May 30, 2017·Nihon eiseigaku zasshi. Japanese journal of hygiene·Ayako Sumi, Nobumichi Kobayashi
Mar 7, 2019·Clinical Chemistry and Laboratory Medicine : CCLM·Chenbin LiWenxiang Chen
Nov 1, 1991·Clinical and Experimental Immunology·Y van RoodH van Houwelingen

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.