PMID: 9550150Apr 29, 1998Paper

Circuitry and role of substance P-immunoreactive neurons in the primate retina

The Journal of Comparative Neurology
N Cuenca, H Kolb

Abstract

In this paper, we extend our previous light microscopic (LM) study of substance P (SP)-containing amacrine and ganglion cell types of the human retina (Cuenca et al. [1995] J. Comp. Neurol. 356:491-504) to an electron microscopic (EM) and confocal-imaging study in order to reveal synaptic circuitry and putative input and output neurons. SP-immunoreactive (-IR) amacrine cells in primate retina are typically wide-field cells with large cell bodies occurring in normal or displaced positions relative to the inner plexiform layer (IPL). Their main dendrites bear many spines and are monostratified in stratum 3 (S3) of the IPL. Axon-like processes arise from dendrites close to the cell body and run for hundreds of microns at the same level as the dendrites, thus forming a relatively dense plexus in S3 of the IPL. SP-IR axon processes also climb to S1 to surround some amacrine cell bodies, and others pass into the outer plexiform layer (OPL). Still other axons run down to the ganglion cell layer, where they encircle SP-IR ganglion cells and pass on to end in the nerve fiber layer. The SP-IR ganglion cell types have large cell bodies (20-22 microm diameter) and dendrites that costratify in S3 among the SP-IR amacrine cell processes. Dou...Continue Reading

References

Feb 22, 1992·The Journal of Comparative Neurology·E V Famiglietti
Apr 8, 1992·The Journal of Comparative Neurology·H KolbS K Fisher
Jun 1, 1992·Visual Neuroscience·G S Ayoub, G Matthews
Feb 22, 1992·The Journal of Comparative Neurology·E V Famiglietti
Dec 1, 1991·Visual Neuroscience·R G Pourcho, M T Owczarzak
May 22, 1991·The Journal of Comparative Neurology·R G Pourcho, M T Owczarzak
Nov 15, 1990·The Journal of Comparative Neurology·D M Dacey
Nov 15, 1990·The Journal of Comparative Neurology·A P Mariani
Jun 1, 1990·Journal of Neurocytology·H KolbL Dekorver
Sep 22, 1988·The Journal of Comparative Neurology·R G Pourcho, D J Goebel
Jan 8, 1985·The Journal of Comparative Neurology·S YazullaC L Zucker
Jun 8, 1989·The Journal of Comparative Neurology·D M Dacey
Oct 1, 1988·The Journal of Comparative Neurology·A P Mariani, J N Hokoc
Jan 1, 1989·The Journal of Comparative Neurology·M H Chun, H Wässle
Jan 1, 1988·Annual Review of Neuroscience·J E Maggio
Oct 23, 1981·Neuroscience Letters·E Dick, R F Miller
Feb 1, 1983·The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society·W D EldredS Yazulla
Dec 2, 1982·Brain Research·R G Pourcho
Oct 22, 1994·The Journal of Comparative Neurology·U GrünertH Wässle
Jun 12, 1995·The Journal of Comparative Neurology·N CuencaH Kolb
Sep 22, 1993·The Journal of Comparative Neurology·U Grünert, H Wässle
Aug 26, 1996·The Journal of Comparative Neurology·P J ShughrueI Merchenthaler
Nov 1, 1996·Experimental Brain Research·A KondohT Sugimoto
Jan 16, 1997·Brain Research·S Reuss, K Decker
Oct 1, 1991·The European Journal of Neuroscience·B. B. Boycott, H. Wässle

❮ Previous
Next ❯

Citations

Nov 2, 2014·Journal of Neuroinflammation·Agustina NoaillesNicolás Cuenca
Oct 16, 2002·The Journal of Comparative Neurology·Béla Völgyi, Stewart A Bloomfield
Jul 12, 2011·Neurobiology of Disease·Julián Esteve-RuddNicolás Cuenca
Oct 8, 2008·The Journal of Comparative Neurology·Gema C Martínez-NavarreteNicolás Cuenca
Jun 10, 2010·The Journal of Comparative Neurology·Shannon K GallagherJozsef Vigh
Jul 16, 2013·The Journal of Comparative Neurology·Felix WeltzienUlrike Grünert
Dec 2, 2004·Brain Research. Brain Research Reviews·Fernando Torrealba, Maria Angélica Carrasco
Sep 8, 2006·Peptides·Eduard SchmidJosef Troger
Oct 2, 2012·Experimental Eye Research·Iván Fernandez-BuenoNicolás Cuenca
Aug 22, 2001·Microscopy Research and Technique·E A Debski
Apr 15, 2006·The Journal of Comparative Neurology·Theresa Puthussery, Erica L Fletcher
Jun 14, 2005·The Journal of Comparative Neurology·Tae-Hoon KangMyung-Hoon Chun
Feb 17, 2006·Journal of Neurophysiology·Robert F MillerToby J Velte

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.