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Circular binary segmentation for the analysis of array-based DNA copy number data

Biostatistics

Oct 1, 2004

Adam B OlshenMichael H Wigler

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Abstract

DNA sequence copy number is the number of copies of DNA at a region of a genome. Cancer progression often involves alterations in DNA copy number. Newly developed microarray technologies enable simultaneous measurement of copy number at thousands of sites in a genome. We have developed ...read more

Mentioned in this Paper

DNA Sequence
Gene Dosage
Breast Cancer Cell
In Silico
Tumor Progression
Biologic Segmentation
Cancer Progression
Cdna Microarrays
Mammary Neoplasms, Human
Cell Line, Tumor
2
734
Paper Details
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Circular binary segmentation for the analysis of array-based DNA copy number data

Biostatistics

Oct 1, 2004

Adam B OlshenMichael H Wigler

PMID: 15475419

DOI: 10.1093/biostatistics/kxh008

Abstract

DNA sequence copy number is the number of copies of DNA at a region of a genome. Cancer progression often involves alterations in DNA copy number. Newly developed microarray technologies enable simultaneous measurement of copy number at thousands of sites in a genome. We have developed ...read more

Mentioned in this Paper

DNA Sequence
Gene Dosage
Breast Cancer Cell
In Silico
Tumor Progression
2
734
Paper Details
References
  • References
  • Citations822
  • References currently unavailable

    We're still populating references for this paper, please check back later.
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  • Citations822
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