PMID: 7380603Mar 1, 1980

Circular dichroism spectra of cleavage fragments of soybean trypsin-chymotrypsin inhibitor

International Journal of Peptide and Protein Research
Y BirkT A Bewley

Abstract

Circular dichroism spectra of biologically active fragments of Bowman-Birk soybean inhibitor have been determined in acidic, neutral, and alkaline conditions. Neither fragment showed evidence of alpha-helix or beta-structure. Negative dichroism above 260nm has been assigned in both fragments primarily to disulfide bonds, with a minor contribution from tyrosine in a hydrophilic environment. The individual spectra of these fragments, and their sum between 230 and 340 nm have been compared with the spectra of the intact inhibitor and several structurally related proteins. Possible interactions which may give rise to CD bands in this region are discussed.

References

Jan 1, 1979·International Journal of Peptide and Protein Research·P SmirnoffS W Applebaum
Nov 1, 1978·International Journal of Peptide and Protein Research·T A Bewley, Y Birk
May 3, 1977·Biochemistry·Y H ChenJ T Yang
Jan 1, 1977·International Journal of Peptide and Protein Research·V A Eterović, P A Ferchmin
Sep 1, 1976·Proceedings of the National Academy of Sciences of the United States of America·B W LowJ S Richardson
Dec 1, 1975·Archives of Biochemistry and Biophysics·L A Holladay, D Puett
Aug 26, 1975·Biochemistry·C J Menendez-Botet, E Breslow
Aug 1, 1974·Archives of Biochemistry and Biophysics·T A BewleyC H Li
Jan 1, 1974·CRC Critical Reviews in Biochemistry·E H Strickland
Oct 31, 1973·Journal of the American Chemical Society·R Nagarajan, R W Woody
Jun 28, 1968·Annals of the New York Academy of Sciences·Y Birk
Oct 21, 1968·Biochimica Et Biophysica Acta·C C YangK Hamaguchi
Apr 1, 1968·Journal of Biochemistry·K IkedaT Ikenaka
Nov 1, 1964·Biochemistry·S BEYCHOK, G D FASMAN
Jan 1, 1952·Advances in Protein Chemistry·G H BEAVEN, E R HOLIDAY

Citations

Feb 1, 1985·International Journal of Peptide and Protein Research·Y Birk

Related Concepts

Avazyme
Circular Dichroism, Vibrational
Hydrogen-Ion Concentration
Peptide Fragments
Trypsin Inhibitor, Bowman-Birk Soybean
Trypsin Inhibitors

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