PMID: 2894383Jan 1, 1988

Circulating antibody detection in human serum to mosquito salivary gland proteins by the avidin-biotin-peroxidase technique

Journal of the American Academy of Dermatology
N S PenneysJ W Knight

Abstract

Serum was collected from individuals with little, average, or extensive exposure to mosquito bites for determination of the presence of circulating antibodies to mosquito salivary gland proteins. Intensity of exposure was determined by mosquito-bite and exposure history. Sections cut through the thorax of four different species of mosquitoes, locally prevalent in South Florida, were exposed to serum and developed for antibody binding with the use of the avidin-biotin-peroxidase immunohistochemical technique. In subjects with histories of little or average exposure to mosquitoes, binding was observed that appeared to be species-specific; in subjects with extensive exposures, little antibody binding to salivary gland was noted. We hypothesize that suppression of the humoral immune response is an adaptive mechanism in response to significant exposures of mosquito salivary gland antigens.

References

Jun 7, 2003·Current Allergy and Asthma Reports·Jeffrey G Demain
Sep 1, 1996·Annals of Allergy, Asthma & Immunology : Official Publication of the American College of Allergy, Asthma, & Immunology·Z PengF E Simons
Apr 27, 2000·Allergy·M W Greaves
Aug 6, 2004·International Journal of Hematology·Keiko AsakuraYasuo Ikeda
Nov 12, 2014·The American Journal of Tropical Medicine and Hygiene·Christine KingJosé A Stoute
Sep 1, 1991·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·T ReunalaT Palosuo
Nov 1, 1990·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·T ReunalaT Palosuo

Citations

Jan 31, 1977·Journal of Medical Entomology·W A NelsonJ E Keirans
Jan 1, 1985·International Archives of Allergy and Applied Immunology·K AilusT Reunala
Dec 1, 1969·Canadian Journal of Biochemistry·W H NewsomeA S West
Dec 1, 1961·Proceedings of the Society for Experimental Biology and Medicine·E BENJAMINIL KARTMAN
Jan 1, 1965·International Archives of Allergy and Applied Immunology·A B WILSON, A N CLEMENTS

Related Concepts

Procedure to Identify Antibody
Salivary Peptides
Peroxidases
Humoral Immunity
Antibody Formation
Insect Sting
Visual Suppression
Antigens
Antigen-Antibody Reactions
Biotin

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