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Circulating concentrations of insulin-like growth factor-I and risk of breast cancer

Lancet

May 21, 1998

Susan E HankinsonMichael N Pollak

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PubMed

Abstract

Insulin-like growth factor (IGF)-I, a mitogenic and antiapoptotic peptide, can affect the proliferation of breast epithelial cells, and is thought to have a role in breast cancer. We hypothesised that high circulating IGF-I concentrations would be associated with an increased risk of br...read more

Mentioned in this Paper

Insulin-Like Growth Factor I
Growth Hormone Activity
Igfbp3
Premenopausal Symptoms
Squamous Transitional Epithelial Cell Count
Somatomedins
Menopause
Insulin-Like Growth Factor Binding Protein 3
Logistic Regression
Postmenopause
10
205
Paper Details
References
  • References25
  • Citations810
123
  • References25
  • Citations810
12345...

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Circulating concentrations of insulin-like growth factor-I and risk of breast cancer

Lancet

May 21, 1998

Susan E HankinsonMichael N Pollak

PMID: 9593409

DOI: 10.1016/s0140-6736(97)10384-1

Abstract

Insulin-like growth factor (IGF)-I, a mitogenic and antiapoptotic peptide, can affect the proliferation of breast epithelial cells, and is thought to have a role in breast cancer. We hypothesised that high circulating IGF-I concentrations would be associated with an increased risk of br...read more

Mentioned in this Paper

Insulin-Like Growth Factor I
Growth Hormone Activity
Igfbp3
Premenopausal Symptoms
Squamous Transitional Epithelial Cell Count
Somatomedins
Menopause
Insulin-Like Growth Factor Binding Protein 3
Logistic Regression
Postmenopause
10
205

Feeds With Similar Papers

General Medical Journal eTOCs

Discover the latest medical research in this collection of the top medical journals.

Hormone-Related Cancers

This feed focuses on hormone-related cancers including cancer of the breast, endometrium, ovary, prostate, testis, thyroid, and bone, all of which share unique mechanisms of carcinogenesis. Here is the latest research.

Related Papers

Drug and Chemical Toxicology

Role of prolactin in chloro-S-triazine rat mammary tumorigenesis

Drug and Chemical ToxicologyNovember 9, 2000
J C O'ConnorJ C Cook
Paper Details
References
  • References25
  • Citations810
123
  • References25
  • Citations810
12345...

Download from

Publisher
PubMed
/papers/circulating-concentrations-of-insulin-like-growth/9593409