Circulating fatty acid profiles in response to three levels of dietary omega-3 fatty acid supplementation in horses

Journal of Animal Science
S S KingK L Jones

Abstract

Fatty acids of the n-3 type confer health benefits to humans and other species. Their importance to equine physiology could include improved exercise tolerance, decreased inflammation, and improved reproductive function. The circulating fatty acid profile and the acquisition and washout of fatty acids in response to n-3 supplementation were determined for horses in the current study. A fatty acid supplement high in eicosapentaenoic (EPA) and docosahexaenoic (DHA) acid was fed to deliver EPA plus DHA at 0 (control), 10, 20, or 40 g/d to 16 mares (n = 4/group) for 28 d. Plasma was collected at -11, 3, 7, 10, 16, 23, 30, 37, 44, 70, and 87 d relative to the beginning of supplementation. Plasma was analyzed for the presence of 35 fatty acids by gas chromatography. Plasma EPA and DHA increased (P < 0.05) in a dose-responsive manner by 3 d of feeding and reached peak concentrations by 7 d. Peak EPA and DHA concentrations of the 40 g/d supplement group were approximately 13x and 10x those of controls, respectively. Plasma EPA and DHA demonstrated a steep decline (P < 0.05) from peak values by 9 d after cessation of supplementation and were near presupplementation values by 42 d. Omega-3 supplementation also increased (P < 0.05) concen...Continue Reading

References

Feb 12, 2000·Prostaglandins, Leukotrienes, and Essential Fatty Acids·D R Abayasekara, D C Wathes
Aug 7, 2001·Prostaglandins, Leukotrienes, and Essential Fatty Acids·P UrquhartA Nicolaou
Dec 14, 2002·Journal of the American College of Nutrition·Artemis P Simopoulos
Oct 16, 2004·Journal of Animal Science·C I O'ConnorS Hayes
Nov 3, 2005·American Journal of Veterinary Research·Amelia S MunstermanSteven E Weisbrode
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Aug 22, 2006·The American Journal of Cardiology·Jennifer G Robinson, Neil J Stone

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Citations

Apr 16, 2016·Journal of Animal Physiology and Animal Nutrition·S K M MéloH C Manso Filho
Jul 21, 2015·Journal of Animal Physiology and Animal Nutrition·T N Ross-JonesJ Black
Sep 14, 2018·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Sabri Ahmed RialCatherine Mounier
Apr 19, 2021·Metabolomics : Official Journal of the Metabolomic Society·Undine ChristmannPaul L Wood
Aug 12, 2021·Anais Da Academia Brasileira De Ciências·Jesús A S ViafaraJosé C DE Souza

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