PMID: 7449074Jul 1, 1980Paper

Circulating immune complexes in bronchial asthma

Clinical Allergy
L StendardiM J Debisschop

Abstract

Soluble immune complexes were detected by a sold phase Clq binding assay in forty-two out of 106 well studied asthmatic patients (39.6%) and in eleven out of 145 age-matched controls (8%; P < 0.01). Clinical significance of immune complexes has been evaluated by comparing the following parameters in patients with and without such complexes: age, sex, duration of disease, IgE-mediated allergy (RAST, skin test), precipitins (Aspergillus, Candida albicans, Thermoactinomycetes), corticodependency, lung function tests, associated symptoms (hivernal bronchitis, urticaria, eczema,...), desenstization treatment, serum concentration in immunoglobulin in G, A, M and E. Immune complexes were found more frequently in female than in male patients. The prevalence of immune complexes was higher in patients treated by hyposensitization therapy and in cases with precipitating antibodies against thermophilic actinomycetes and Aspergillus.

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Citations

Mar 1, 1989·Journal of Clinical Immunology·K H Hsieh
May 1, 1988·Journal of Clinical Immunology·K H Hsieh
Jul 31, 2001·Annals of Allergy, Asthma & Immunology : Official Publication of the American College of Allergy, Asthma, & Immunology·R F LockeyS C Bukantz
Feb 1, 1984·The Journal of Allergy and Clinical Immunology·W J Stevens, C H Bridts
May 1, 1982·Clinical Allergy·P H Kaad, P A Ostergaard
Sep 1, 1983·Clinical Allergy·G MarcerG Mastrangelo
May 1, 1993·Arthritis and Rheumatism·E H ChoyG S Panayi
Jan 1, 1984·Microbiology and Immunology·K TasakaY Hamashima
Jan 1, 1989·Critical Reviews in Clinical Laboratory Sciences·T M Phillips
May 1, 2021·Animals : an Open Access Journal From MDPI·Malwina SlowikowskaArtur Niedzwiedz

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