Circulating leptin levels in elderly subjects with and without cerebrovasular disease

Journal of the College of Physicians and Surgeons--Pakistan : JCPSP
Anila JalilFarhan Jalil

Abstract

Serum concentrations of leptin was investigated in 40 patients with ischemic stroke, in context of the size of the lesion and also in 40 non-diseased controls, matched according to age, gender and waist hip ratio. Serum leptin concentrations were determined in ng/ml with ELISA and computer tomography (CT) scan was performed in patients to estimate lesion size in cms. Serum leptin concentrations were found to be significantly higher (p < 0.001) in stroke patients (51.61+1.39), compared with controls (37.76+1.207). Moreover, positive correlation (r=0.93) existed between serum leptin level and infarction size in patients with stroke.

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