PMID: 6963123Jan 1, 1982Paper

Circulating proteins and macromolecular transport across continuous, nonfenestrated endothelium

Annals of the New York Academy of Sciences
E E Schneeberger

Abstract

Experiments are described, using isolated perfused capillaries, fluorocarbon exchanged rats, and endothelial cells in culture, that examine the interaction of circulating proteins with the endothelial surface. A consequence of the interaction of circulating proteins with the endothelial surface is to render the endothelium less permeable to water, small water-soluble molecules, as well as macromolecules. Indirect evidence suggests that this is the result of adsorption of proteins to the glycoprotein coat of endothelial cells. An understanding of the physiochemical basis for this interaction awaits further studies of the chemical composition and properties of molecules constituting the endothelial cell surface.

References

Jan 31, 1967·Proceedings of the Royal Society of London. Series B, Containing Papers of a Biological Character·M A Jennings, L Florey
Jan 1, 1973·Quarterly Journal of Experimental Physiology and Cognate Medical Sciences·J R Levick, C C Michel
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Feb 1, 1978·The Journal of Cell Biology·S L Wissig, M C Williams
Mar 14, 1940·The Journal of Physiology·J F Danielli

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Citations

Mar 1, 1994·Annals of Neurology·C A Thornton, R C Griggs
Feb 1, 1990·Cancer Metastasis Reviews·P N Belloni, R J Tressler
Jul 15, 1987·Biochemical and Biophysical Research Communications·W M PardridgeJ B Eisenberg
Mar 1, 1988·Arteriosclerosis : an Official Journal of the American Heart Association, Inc·A L Baldwin, S Chien
Sep 1, 1985·Arteriosclerosis : an Official Journal of the American Heart Association, Inc·A L Baldwin, S Chien
Aug 1, 1984·Journal of Cellular Physiology·S K WilliamsN J Solenski
Sep 1, 1985·The American Journal of Physiology·W M PardridgeW T Cefalu

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