Circulating tumour cells in head and neck cancers: Biological insights

Journal of Oral Pathology & Medicine : Official Publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology
Vishal RaoPeter A Brennan

Abstract

Tumour metastasis is one of the leading cause of cancer-related mortality. Circulating tumour cells (CTCs) have been implicated in loco-regional and distant metastasis and its role is being extensively studied in various malignancies, including those from the head and neck region. The main challenge in understanding their significance lies in the rarity of these cells in the blood. However, newer technologies have attempted to overcome these pitfalls. This review explores the evolution of CTC research and other related areas, including its biological significance, sustainability within the circulating vascular environment and possible clinical implications.

References

Mar 1, 1973·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·I J Fidler
Oct 27, 2001·Acta Oto-laryngologica·A FerlitoH Hamakawa
Nov 2, 2001·Nature·T ReyaI L Weissman
Jan 12, 2002·Archives of Otolaryngology--head & Neck Surgery·Ari WirtschafterMaria J Worsham
Mar 12, 2003·Proceedings of the National Academy of Sciences of the United States of America·Muhammad Al-HajjMichael F Clarke
Apr 2, 2005·Nature Reviews. Cancer·Michael DeanSusan Bates
Jul 20, 2005·Journal of Clinical Pharmacology·Vera S Donnenberg, Albert D Donnenberg
Aug 27, 2005·The New England Journal of Medicine·Stephan BraunKlaus Pantel
Sep 5, 2006·Cancer Research·Jason J Christiansen, Ayyappan K Rajasekaran
Apr 6, 2007·Endocrine Reviews·Robert R Langley, Isaiah J Fidler
Oct 24, 2007·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Lyndsay HarrisUNKNOWN American Society of Clinical Oncology
Oct 25, 2007·Nature Reviews. Cancer·Julio A Aguirre-Ghiso
Feb 14, 2008·Journal of the National Cancer Institute·Ken Garber
Jun 24, 2008·Cancer Investigation·A Shervington, C Lu
Sep 17, 2008·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Jens KöllermannKlaus Pantel
Jun 3, 2009·The Journal of Clinical Investigation·Raghu Kalluri, Robert A Weinberg
Sep 8, 2009·Nature Medicine·Piyush B GuptaRobert A Weinberg
Dec 22, 2010·Archives of Otolaryngology--head & Neck Surgery·Kris R JatanaJeffrey J Chalmers
Feb 9, 2011·The Journal of Cell Biology·Min YuDaniel A Haber
Mar 3, 2011·International Journal of Cancer. Journal International Du Cancer·Robert R Langley, Isaiah J Fidler
Mar 8, 2011·Cell·Douglas Hanahan, Robert A Weinberg
Jul 27, 2012·International Journal of Cancer. Journal International Du Cancer·Michael Herman Chui
Aug 22, 2012·Clinical Cancer Research : an Official Journal of the American Association for Cancer Research·Liling ZhangKlaus Pantel
Mar 23, 2013·Cancer Cell·Jean Paul Thiery, Chwee Teck Lim
Jul 16, 2014·Proceedings of the National Academy of Sciences of the United States of America·Myriam LabelleRichard O Hynes
Mar 20, 2015·American Journal of Physiology. Cell Physiology·Michael R KingOwen J T McCarty
Apr 18, 2015·Journal of Hematology & Oncology·Axel SchulenburgPeter Valent
Jun 9, 2015·Oncogene·K Pantel, M R Speicher
Aug 12, 2015·Clinical & Translational Oncology : Official Publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico·Q LvY Mao
Nov 5, 2015·Advances in Experimental Medicine and Biology·Evi S LianidouAreti Strati
Jan 20, 2016·The Journal of Cell Biology·Elena Scarpa, Roberto Mayor
Aug 19, 2017·Theranostics·Lichan ChenZigang Dong
Mar 8, 2018·Journal of Dental Research·T Nonaka, D T W Wong
Oct 27, 2018·Nature Cell Biology·Erica T GoddardCyrus M Ghajar
Oct 29, 2018·Advances in Experimental Medicine and Biology·Allison K SimiCeleste M Nelson

❮ Previous
Next ❯

Citations


❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Recent Results in Cancer Research. Fortschritte Der Krebsforschung. Progrès Dans Les Recherches Sur Le Cancer
Francesca ChemiGed Brady
© 2022 Meta ULC. All rights reserved