PMID: 15333714Aug 31, 2004Paper

Cis-9, trans-11 and trans-10, cis-12 conjugated linoleic acid isomers do not modify body composition in adult sedentary or exercised rats

The Journal of Nutrition
Philippe Patureau MirandYves Chilliard

Abstract

Dietary CLA isomers were shown to reduce adipose tissues in growing animals, mainly in mice, but their effects in adult animals remain unclear. This study was conducted to determine whether these effects depend on the isomer fed, on physical activity, or on the initial level of body fat. Male Wistar rats (4 mo old) were fed for 6 wk diets containing either no CLA, the cis-9, trans-11 CLA isomer (10 g/kg), the trans-10, cis-12 CLA isomer (10 g/kg), or both isomers (10 g/kg each). Half of the rats were assigned to exercise by treadmill running (1 h/d, 22 m/min). The initial body fat level was normal (12.7%) in a first trial, and high (18.9%) in a second trial. Chemical and anatomical body compositions were determined by chemical analysis and organ dissection. In both trials, the CLA diets, whatever the isomer, had no effect on food intake and body weight changes, on body chemical composition (fat, protein and water contents or gains), or on the body anatomical composition (weights or gains in epididymal and perirenal adipose tissues, in liver and in 4 muscles). There was no interaction between CLA treatment and physical activity. In conclusion, adult male rats do not appear to be responsive to the fat-to-lean partitioning effect ...Continue Reading

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Citations

Jan 16, 2007·Journal of Physiology and Biochemistry·V NavarroM P Portillo
Jan 16, 2007·Journal of Physiology and Biochemistry·V NavarroM P Portillo
May 11, 2007·The American Journal of Clinical Nutrition·Leah D WhighamDale A Schoeller
Jun 9, 2017·Tropical Animal Health and Production·Santi Devi UpadhayaIn Ho Kim
Dec 16, 2006·Reproduction, Nutrition, Development·Philippe Patureau MirandYves Chilliard
May 19, 2007·Applied Physiology, Nutrition, and Metabolism = Physiologie Appliquée, Nutrition Et Métabolisme·A Brianne ThrushDavid J Dyck
Aug 21, 2010·Archives of Animal Nutrition·Henry JørgensenKirsten Jakobsen
Jul 22, 2009·The British Journal of Nutrition·Jonatan MirandaMaría Puy Portillo
May 3, 2006·The Journal of Nutritional Biochemistry·Arunabh BhattacharyaGabriel Fernandes
Feb 27, 2007·Molecular and Cellular Endocrinology·P Pérez-MatuteM J Moreno-Aliaga
Mar 21, 2007·The Journal of Nutritional Biochemistry·Aparna PurushothamMartha A Belury

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