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Cis-regulatory Elements and Human Evolution

bioRxiv

May 28, 2014

Adam Siepel, Leonardo Arbiza

Abstract

Modification of gene regulation has long been considered an important force in human evolution, particularly through changes to cis -regulatory elements (CREs) that function in transcriptional regulation. For decades, however, the study of cis -regulatory evolution was severely limited ...read more

Mentioned in this Paper

CST8 gene
Cst8 protein, rat
Species
Genetic Polymorphism
SREBP Signaling Pathway
Primates
Regulatory Sequences, Nucleic Acid
Research
Study
Location
11
40
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Cis-regulatory Elements and Human Evolution

bioRxiv

May 28, 2014

Adam Siepel, Leonardo Arbiza

PMID: 990005652

DOI: 10.1101/005652

Abstract

Modification of gene regulation has long been considered an important force in human evolution, particularly through changes to cis -regulatory elements (CREs) that function in transcriptional regulation. For decades, however, the study of cis -regulatory evolution was severely limited ...read more

Mentioned in this Paper

CST8 gene
Cst8 protein, rat
Species
Genetic Polymorphism
SREBP Signaling Pathway
Primates
Regulatory Sequences, Nucleic Acid
Research
Study
Location
11
40

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