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Cis-regulatory elements and human evolution

bioRxiv

May 28, 2014

Adam C Siepel, Leonardo Arbiza

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Abstract

Modification of gene regulation has long been considered an important force in human evolution, particularly through changes to cis-regulatory elements (CREs) that function in transcriptional regulation. For decades, however, the study of cis-regulatory evolution was severely limited by...read more

Mentioned in this Paper

Gene Polymorphism
Species
Transcriptional Regulation
Study
Genetic Polymorphism
Genome
CST8 gene
SREBP Signaling Pathway
Research
Regulatory Sequences, Nucleic Acid
11
40
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  • Cis-regulatory elements and human evolution

    bioRxiv

    May 28, 2014

    Adam C Siepel, Leonardo Arbiza

    PMID: 990005652

    DOI: 10.1101/005652

    Abstract

    Modification of gene regulation has long been considered an important force in human evolution, particularly through changes to cis-regulatory elements (CREs) that function in transcriptional regulation. For decades, however, the study of cis-regulatory evolution was severely limited by...read more

    Mentioned in this Paper

    Gene Polymorphism
    Species
    Transcriptional Regulation
    Study
    Genetic Polymorphism
    11
    40

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