cis Versus trans -Azobenzene: Precise Determination of NMR Parameters and Analysis of Long-Lived States of 15 N Spin Pairs

Applied Magnetic Resonance
Kirill F SheberstovAlexandra V Yurkovskaya

Abstract

We provide a detailed evaluation of nuclear magnetic resonance (NMR) parameters of the cis- and trans-isomers of azobenzene (AB). For determining the NMR parameters, such as proton-proton and proton-nitrogen J-couplings and chemical shifts, we compared NMR spectra of three different isotopomers of AB: the doubly 15N labeled azobenzene, 15N,15N'-AB, and two partially deuterated AB isotopomers with a single 15N atom. For the total lineshape analysis of NMR spectra, we used the recently developed ANATOLIA software package. The determined NMR parameters allowed us to optimize experiments for investigating singlet long-lived spin states (LLSs) of 15N spin pairs and to measure LLS lifetimes in cis-AB and trans-AB. Magnetization-to-singlet-to-magnetization conversion has been performed using the SLIC and APSOC techniques, providing a degree of conversion up to 17 and 24% of the initial magnetization, respectively. Our approach is useful for optimizing the performance of experiments with singlet LLSs; such LLSs can be exploited for preserving spin hyperpolarization, for probing slow molecular dynamics, slow chemical processes and also slow transport processes.

References

Mar 12, 2004·Journal of the American Chemical Society·Alessandro CembranGiorgio Orlandi
May 20, 2004·Journal of the American Chemical Society·Marina Carravetta, Malcolm H Levitt
Jun 1, 2004·Physical Review Letters·Marina CarravettaMalcolm H Levitt
Jul 17, 2010·Progress in Nuclear Magnetic Resonance Spectroscopy·Giuseppe Pileio
Sep 22, 2010·Proceedings of the National Academy of Sciences of the United States of America·Giuseppe PileioMalcolm H Levitt
Feb 15, 2011·Physical Chemistry Chemical Physics : PCCP·Michael C D Tayler, Malcolm H Levitt
Oct 20, 2011·Chemical Society Reviews·H M Dhammika Bandara, Shawn C Burdette
Jun 14, 2012·Journal of the American Chemical Society·María Belén FranzoniKerstin Münnemann
Sep 29, 2012·Beilstein Journal of Organic Chemistry·Estíbaliz Merino, María Ribagorda
Mar 16, 2013·Journal of the American Chemical Society·Giuseppe PileioMalcolm H Levitt
Jul 25, 2013·Physical Chemistry Chemical Physics : PCCP·Alexey S KiryutinNikita N Lukzen
Sep 11, 2013·Physical Chemistry Chemical Physics : PCCP·M B FranzoniK Münnemann
Nov 12, 2013·Physical Review Letters·Stephen J DeVienceMatthew S Rosen
Sep 18, 2014·Journal of the American Chemical Society·Kevin ClaytorWarren S Warren
Oct 10, 2014·The Journal of Chemical Physics·Yesu FengWarren S Warren
Jan 30, 2015·Angewandte Chemie·Gabriele StevanatoMalcolm H Levitt
Jan 31, 2015·Physical Chemistry Chemical Physics : PCCP·Gabriele StevanatoMalcolm H Levitt
Jul 5, 2012·The Journal of Physical Chemistry Letters·Alexey S KiryutinHans-Martin Vieth
Nov 4, 2015·Journal of Magnetic Resonance·Alexey S KiryutinKonstantin L Ivanov
Oct 21, 2016·Journal of Magnetic Resonance·D A CheshkovV A Chertkov
Oct 18, 2016·Journal of Magnetic Resonance·Andrey N PravdivtsevKonstantin L Ivanov
Oct 28, 2016·The Journal of Physical Chemistry. B·Alexey S KiryutinKonstantin L Ivanov
Mar 12, 2017·Progress in Nuclear Magnetic Resonance Spectroscopy·Giuseppe Pileio
Sep 20, 2017·Journal of Magnetic Resonance·B KharkovA Jerschow

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Citations

Feb 28, 2019·Physical Chemistry Chemical Physics : PCCP·Kirill F SheberstovKonstantin L Ivanov
Aug 8, 2019·Physical Chemistry Chemical Physics : PCCP·Ivan V ZhukovKonstantin L Ivanov
Dec 23, 2019·The Journal of Chemical Physics·Bogdan A RodinKonstantin L Ivanov
Dec 29, 2019·Scientific Reports·Kirill F SheberstovAlexandra V Yurkovskaya
May 3, 2020·The Journal of Chemical Physics·Bogdan A RodinMalcolm H Levitt
May 2, 2021·Chemphyschem : a European Journal of Chemical Physics and Physical Chemistry·Kirill F SheberstovAlexandra V Yurkovskaya
Dec 3, 2021·Chemistry : a European Journal·Shengjun YangStefan Glöggler

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Methods Mentioned

BETA
nuclear magnetic resonance
NMR

Software Mentioned

APSOC GUI
ANATOLIA
APSOC
SLIC

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