PMID: 11918067Mar 29, 2002Paper

CJ-15,696 and its analogs, new furopyridine antibiotics from the fungus Cladobotryum varium: fermentation, isolation, structural elucidation, biotransformation and antibacterial activities

The Journal of Antibiotics
Shinichi SakemiYasuhiro Kojima

Abstract

CJ-15,696 and 7 novel furopyridine antibiotics were isolated from the fungus Cladobotryum varium CL12284. Their structures were determined by X-ray crystallography and spectral analysis. Three biotransformed analogs were also prepared from CJ-15,696. CJ-15,696 showed moderate activity against various Gram-positive bacteria including some drug resistant strains such as methicillin resistant Staphylococcus aureus (MRSA).

Citations

Aug 12, 2020·Angewandte Chemie·Zhuan ZhangYi Tang
Dec 2, 2006·Chemical & Pharmaceutical Bulletin·Takashi FukudaSatoshi Omura
Jul 7, 2019·Marine Drugs·Shan-Chong ChenWei-Min Zhang
Jan 14, 2021·Journal of Natural Products·Tao ZhouYasuhiro Igarashi
Feb 11, 2011·Organic Letters·Tomoko MiyagawaTohru Nagamitsu
Mar 1, 2003·The Journal of Organic Chemistry·Yunjiang FengMurray H G Munro

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