Classical cardiovascular risk factors and all-cause mortality in rural Cameroon

QJM : Monthly Journal of the Association of Physicians
Andre Pascal Kengne, Paschal Awah

Abstract

High levels of cardiovascular risk factors have been reported in rural Africa. How these translate into major outcomes remain unknown. To assess the association between selected risk factors and all-cause mortality in rural Cameroon. Nine-year's prospective cohort study. The 9-year's vital status was ascertained for 350 participants screened for cardiovascular risk factors in Bafut, Cameroon in 1998. Cox models were used to compute the hazard ratio (HR) and 95% confidence interval (CI) for selected risk factors. Vital status was available for all participants, except 22 (6.3%) who were excluded from analyses. At baseline, compared with women, men had significantly higher waist-to-hip ratio, were more likely to be ex- or current smokers and alcohol consumers (all P < or = 0.008). The total duration of follow-up was 2771 person-years. This duration was longer for women (P = 0.04). During follow-up 47 deaths were recorded, 31 (66%) in men (P = 0.023). In multivariate Cox analyses, age, male gender, current smoking, systolic blood pressure and fasting capillary glucose were significant predictors of total mortality during follow-up. Gender, smoking, fasting capillary glucose, blood pressures and age are potential determinants of ov...Continue Reading

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Citations

Nov 25, 2011·Globalization and Health·Justin B Echouffo-Tcheugui, Andre P Kengne
Jul 10, 2010·International Journal of Environmental Research and Public Health·Alain LekoubouAndre Pascal Kengne
Dec 22, 2011·The Pan African Medical Journal·Clarisse Noël Ayina Ayina LissockLaurent Serge Ngoa Etoundi
Oct 31, 2012·Cardiovascular Journal of Africa·Bridget AdeboyeCatherine Rolland
Oct 13, 2009·The Journal of Clinical Hypertension·Andre P KengneJean-Claude Mbanya
Mar 11, 2015·Nature Reviews. Cardiology·Dong ZhaoYue Qi

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