Abstract
Sixty-five clinical isolates of coagulase-negative, methicillin-resistant staphylococci have been classified as Staphylococcus epidermidis (63.0%), "phosphatase-negative S. epidermidis" (12.3%), coagulase-negative Staphylococcus aureus (6.2%), Staphylococcus hemolyticus (6.2%), Staphylococcus hominis (3.1%), and Staphylococcus warneri (1.5%). Five of the organisms (7.7%) could not be classified with certainty as currently recognized species. Novobiocin resistance was encountered in eight of the strains, but these were not classified as the accepted novobiocin-resistant staphylococcal species. Some differences in antibiotic resistance patterns to those typical of methicillin-resistant S. aureus were noted in that, although 29 strains were resistant to methicillin, penicillin, sulfamethizole, streptomycin, and tetracycline, the remainder of the strains were sensitive to streptomycin or tetracycline or both. In a majority of the strains (42 of 65), methicillin susceptibility testing by the disk method at 30 or at 37 degrees C in the presence of NaCl did not appear to enhance resistance expression. Most of the strains produced beta-lactamase (EC 3.5.2.6), but none of the 21 strains tested produced enterotoxin B.
References
Nov 1, 1977·The Journal of Antimicrobial Chemotherapy·L D Sabath
Dec 1, 1978·Journal of Bacteriology·B J WilkinsonL D Sabath
Jan 1, 1979·Antimicrobial Agents and Chemotherapy·S SchaeflerD Jones
Jan 1, 1975·Journal of Clinical Microbiology·W E Kloos, K H Schleifer
May 1, 1977·Infection and Immunity·J J Iandolo, W M Shafer
Nov 1, 1978·Southern Medical Journal·W T SiebertT W Williams
Sep 1, 1979·Infection and Immunity·W M Shafer, J J Iandolo
Apr 1, 1978·Journal of General Microbiology·J L Gramoli, B J Wilkinson
Sep 1, 1978·Antimicrobial Agents and Chemotherapy·G L Archer
May 1, 1976·Journal of Medical Microbiology·F H KayserP Santanam
Mar 1, 1975·Bacteriological Reviews·R W Lacey
Mar 1, 1975·Journal of Clinical Microbiology·K H Schleifer, W E Kloos
Apr 1, 1967·The Journal of Pathology and Bacteriology·C A Pennock, R B Huddy
Nov 1, 1973·Journal of Medical Microbiology·R W Lacey, J Grinsted
Aug 1, 1952·American Journal of Clinical Pathology·T H HAIGHT, M FINLAND
Citations
Jul 31, 1998·The American Journal of Medicine·M DowzickyM Pease
Aug 1, 1983·Journal of Clinical Microbiology·G D ChristensenE H Beachey
Dec 1, 1983·Journal of Clinical Microbiology·A E GrasmickD A Bruckner
May 1, 1992·Journal of Clinical Microbiology·C A GuzmànG Satta
Jun 1, 1984·Journal of Clinical Microbiology·P E VaraldoA Repetto
Sep 1, 1982·Journal of Clinical Microbiology·W E Kloos, J F Wolfshohl
Mar 1, 1982·Antimicrobial Agents and Chemotherapy·S B Price, D J Flournoy
Sep 1, 1986·Journal of Clinical Microbiology·G L WoodsC C Knapp
Nov 1, 1987·Antimicrobial Agents and Chemotherapy·M V MadirajuB J Wilkinson
Mar 1, 1982·Journal of Clinical Microbiology·R H EngD Armstrong
May 1, 1986·Journal of Clinical Microbiology·P N RatherB J Wilkinson
Feb 1, 1983·Journal of Clinical Microbiology·L E NicolleG K Harding