Classification, microbiology and treatment of diabetic foot infections

Journal of Wound Care
Reza GhotaslouNaser Alizadeh

Abstract

Diabetic foot ulcers (DFUs) are a common complication of type-1 and type-2 diabetes. About 10-15% of patients with diabetes develop foot ulcers. A validated foot ulcer classification system that will support the development of treatment strategis is necessary for clinicians managing DFUs. More than 10 classification systems have been described by researchers. Another important aspect of the management of DFUs is the proper identification of causative pathogens that trigger infections. While conventional diagnostic methods, such as swabs, cultures and biopsies are more widely used, novel molecular techniques have been exploring bacterial identification and quantification. Knowledge of the microbial aetiologies in diabetic foot infections, and understanding of antibiotic resistance, is critical for the effective management and treatment of these infected wounds. Initial antibiotic regimens are usually selected empirically. A set of common principles may help avoid selecting either an unnecessarily broad or inappropriately narrow antibiotic treatment regimen. In this review we provide a comprehensive summary and description of classification systems of diabetic foot infections, and a comprehensive discussion of microbiology.

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Citations

Jun 6, 2019·Journal of Wound Care·Robert GalianoUNKNOWN Sanuwave Trial Investigators
Jul 16, 2020·Revista do Colégio Brasileiro de Cirurgiões·DÊnisson Guedes PontesLeonardo Pessoa Cavalcante
May 19, 2021·Journal of the American Geriatrics Society·Wahila AlamMay Reed
May 11, 2021·FEMS Microbiology Reviews·Andreu Coello PelegrinAlex van Belkum
Jun 10, 2021·The International Journal of Lower Extremity Wounds·Jiaqi LiuYuedong Shi

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Methods Mentioned

BETA
amputations
amputation
biopsy
biopsies
electrophoresis

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