Classification of bone tumors

European Journal of Radiology
F Bertoni, P Bacchini

Abstract

The classification of bone tumors relies on the cytologic features and products of tumor cells. This classification is reproducible and accepted by pathologists, oncologic surgeons and oncologists. Chondrogenic tumors are the second largest group of bone tumors. Their histologic pattern suggests a relationship to hyaline cartilage. Exostoses, or osteochondromas, represent about 1/3 of chondrogenic lesions. Chondromas are hyaline cartilage tumors which can be found centrally or subperiosteally; they may contain some calcifications and/or ossifications. Chondroblastomas are tumors whose cells produce, at least focally, a matrix similar to hyaline cartilage. Histology of chondromyxoid fibromas shows large or small areas where proliferating cells produce a matrix resembling the hyaline cartilage. Chondosarcomas are tumors whose malignant cells produce a cartilaginous matrix. Most of them occur in previously normal bones; they are classified as conventional or primary chondrosarcomas. Secondary chondrosarcomas result from the malignant transformation of a benign cartilaginous lesion less commonly enchondromas and most commonly osteocartilaginous exostoses, or osteochondromas. Less common variants include dedifferentiated, mesenchyma...Continue Reading

Citations

Nov 10, 2004·International Seminars in Surgical Oncology : ISSO·Peter Fm ChoongRodney Hicks
Sep 11, 2001·Radiologic Clinics of North America·S L Miller, F A Hoffer
Feb 28, 2019·Orthopedics·Anokha A Padubidri, Todd E Bertrand
Nov 17, 2009·The Journal of Urology·Ke-Hung TsuiBenjamin Yat-Ming Yung

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