Classification of Farnsworth-Munsell 100-hue test results in the early treatment diabetic retinopathy study

American Journal of Ophthalmology
Franca B BartonETDRS Research Group

Abstract

To classify and describe clinically meaningful classes of color vision defects using pretreatment Farnsworth-Munsell 100-hue results from the Early Treatment Diabetic Retinopathy Study (ETDRS) patients using standard statistical techniques. The ETDRS was a randomized trial investigating retinal photocoagulation and oral aspirin in diabetic retinopathy. Farnsworth-Munsell (FM) 100-hue test was successfully administered before initiation of study treatment in each eye of 2701 of the 3711 ETDRS patients. Test results were converted into a Fourier series, classified by cluster analysis in the deferred-treatment group of eyes, and verified in the immediate-treatment group of eyes as separate samples. Cluster analysis uncovered thirteen distinct patterns. Pattern A (51% or 1366 of the eyes) showed unimpaired hue discrimination and was comprised of younger patients with no or little macular edema. Pattern B eyes (10% or 262) showed generalized impairment of hue discrimination with no main axis defect. Patterns C (C1, C2, C3), comprising 26% (or 698) of the eyes, showed increasing severity of the yellow-blue diabetic retinopathy defect, associated with increasing mean age and increasing macular edema severity. Patterns D (D1, D2), comp...Continue Reading

Citations

Feb 3, 2012·Journal of Ophthalmic Inflammation and Infection·Peizeng YangAize Kijlstra
Sep 12, 2006·Visual Neuroscience·Claudia Feitosa-SantanaDora F Ventura
Oct 5, 2010·Ophthalmic & Physiological Optics : the Journal of the British College of Ophthalmic Opticians (Optometrists)·Claudia Feitosa-SantanaDora F Ventura
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Oct 7, 2018·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Dolores de FezVicente J Camps

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