Clauemarazoles A-G, seven carbazole alkaloids from the stems of Clausena emarginata

Fitoterapia
Hong-Min XiaDong-Ming Zhang

Abstract

Seven new carbazole alkaloids, clauemarazoles A-G, together with 19 known analogues were isolated from the stems of Clausena emarginata. Their structures were established on the basis of spectroscopic analyses, and the absolute configurations of compounds 1a, 1b, 5a, and 5b were confirmed by their ECD spectroscopy. Compounds 4, 13, 15, and 17 exhibited inhibitory abilities on LPS-induced NO production. Compounds 10-12, 20, 22, and 24 displayed hepatoprotective effects against DL-galactosamine-induced damage in WB-F344 cells.

References

Feb 10, 2011·Journal of Natural Products·Uraiwan SongsiangChavi Yenjai
Mar 1, 2012·Journal of Natural Products·Hang LiuDong-Ming Zhang
Apr 10, 2012·Journal of Natural Products·Wisanu ManeeratSurat Laphookhieo
Jun 6, 2013·Journal of Natural Products·Yan ZhangShi-Shan Yu
Mar 7, 2014·Journal of Natural Products·Hong-Min XiaDong-Ming Zhang
May 7, 2014·Journal of Natural Products·De-Yang ShenTian-Shung Wu
May 9, 2014·Fitoterapia·Jing ShiDong-Ming Zhang
Sep 25, 2014·Journal of Asian Natural Products Research·Hong-Min XiaDong-Ming Zhang

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Citations

Jun 9, 2016·Journal of Asian Natural Products Research·Guo-Qing OuyangDong-Ming Zhang
Jun 13, 2016·Phytochemistry·Hong-Min XiaDong-Ming Zhang
Jul 28, 2016·Chemistry & Biodiversity·Guo-Qing OuyangDong-Ming Zhang
Jul 20, 2019·Journal of Molecular Recognition : JMR·Ying WangJunbiao Chang

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