Clear cell carcinoma of ovary with squamous metaplasia: A unique histopathological observation.

Indian Journal of Medical and Paediatric Oncology : Official Journal of Indian Society of Medical & Paediatric Oncology
Prasenjit DasSandeep R Mathur

Abstract

Squamous metaplasia though is commonly associated with ovarian endometrioid neoplasm, mixed mullerian tumor and Brenner tumors; it has not been described in an ovarian clear cell carcinoma. Unusual presence of squamous islands, either in the form of morules or keratin plaques, may create diagnostic difficulty in a clear cell carcinoma of ovary, and thus the other common associations should be ruled out. Here, we describe a case of clear cell carcinoma of the ovary, with both gross and microscopically identifiable squamous metaplasia. To the best of our knowledge, this is the first report on this rare association and should be documented for wider awareness.

Citations

Jul 2, 2015·Annals of Laboratory Medicine·Hyeyoung LeeKyungja Han

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