Clear cell odontogenic carcinoma with ghost cells and inductive dentin formation - report of a case in the mandible

Journal of Oral Pathology & Medicine : Official Publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology
Yasunori AriyoshiHiromasa Nikai

Abstract

An atypical case of clear cell odontogenic carcinoma occurred in the mandible of a 50-year-old Japanese man. Microscopically, the tumor mainly consisted of clear, glycogen-rich epithelial cell nests, aggressively proliferated in the mandible and invading into the surrounding soft tissues. Within the tumor cell nests, clusters of ghost cells were observed in addition to occasional foci of microcystic degeneration. Hyaline, osteoid or dentinoid-like deposits were also demonstrated adjacent to the tumor cell nests. Dentinal tubules were clearly revealed in some of these structures. Hence, this tumor was regarded as an epithelial neoplasm with odontogenic ectomesenchyme induction.

References

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Citations

Sep 10, 2010·Medical Oncology·Jing ZhangYinzhong Duan
Jun 27, 2013·Journal of Oral and Maxillofacial Pathology : JOMFP·Niharika SwainJay Gopal Ray
Nov 21, 2014·Head and Neck Pathology·Adalberto Mosqueda-TaylorTakashi Takata
Dec 17, 2008·Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics·André ChaineChloé Bertolus
Jul 5, 2008·American Journal of Otolaryngology·Bhishamjit S CheraWilliam M Mendenhall
May 19, 2009·Journal of Oral and Maxillofacial Surgery : Official Journal of the American Association of Oral and Maxillofacial Surgeons·Heiner WerleMax Heiland
Aug 4, 2015·Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology·Adriano Mota LoyolaRicardo Santiago Gomez
Dec 20, 2007·Oral and Maxillofacial Surgery Clinics of North America·Alice E Curran
Dec 20, 2007·Oral and Maxillofacial Surgery Clinics of North America·Lee J Slater
May 20, 2016·Histopathology·Adriano M LoyolaJean N Dos Santos
Jul 8, 2008·Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics·Flávia Caló Aquino XavierSuzana Cantanhede Orsini Machado de Sousa
Mar 16, 2006·Avian Pathology : Journal of the W.V.P.A·Dave Cavanagh
Feb 13, 2020·International Journal of Surgical Pathology·Fernanda Viviane MarianoAdalberto Mosqueda Taylor
Jan 25, 2012·The Journal of Contemporary Dental Practice·Kishore SonawaneSasidhar Singaraju
Jul 1, 2021·National Journal of Maxillofacial Surgery·Anubhav JannuRachana Srinivas
Sep 21, 2021·Oral and Maxillofacial Surgery·Erasmo Bernardo MarinhoFabricio Bitu Sousa
Oct 8, 2021·Head and Neck Pathology·Alberto Jose Peraza LabradorJohn M Wright
Oct 14, 2019·Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology·Rogerio Oliveira GondakCarolina Cavalieri Gomes

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