PMID: 7542673Aug 1, 1995Paper

Clear cell papulosis: report of three cases of a newly recognized disease

Journal of the American Academy of Dermatology
T T KuoM J Chen

Abstract

Clear cell papulosis is a newly described disease. Since the first report in 1987, no other cases have been reported. Our purpose was to describe three more newly identified cases that further characterize this disease. Formalin-fixed and paraffin-embedded biopsy specimens were used for histochemical and immunohistochemical studies. The three patients included two boys and, for the first time, a girl. All three had multiple white papules on the lower part of the abdomen, with or without scattered lesions along the milk lines bilaterally. The main histopathologic finding was the presence of clear cells scattered mainly among the basal cells of the acanthotic epidermis. The clear cells were variably stained by mucicarmine, colloidal iron, alcian blue (pH 2.5), periodic acid-Schiff, the anticytokeratin antibody AE1, carcinoembryonic antigen, epithelial membrane antigen, and gross cystic disease fluid protein-15. Clear cell papulosis is a unique clinicopathologic entity. The clear cells were confirmed to be sweat gland secretory cells by their positive immunostaining with gross cystic disease fluid protein-15. The latter was also present in eccrine sweat gland coil cells. However, whether the clear cells were eccrine or apocrine se...Continue Reading

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Citations

Nov 22, 2001·The American Journal of Surgical Pathology·S F KuanW Recant
Oct 23, 1997·Pediatric Dermatology·Y C KimY W Cinn
Dec 7, 2011·Pediatric Dermatology·Ashley WysongLatanya Benjamin
Dec 31, 1998·Journal of Cutaneous Pathology·T MakinoM Mihara
Jul 8, 2010·Journal of the American Academy of Dermatology·Fang-Wen TsengRosaline Chung-Yee Hui
May 30, 2009·Journal of Cutaneous Pathology·Christine J Ko, Antonio Subtil
Feb 14, 2002·Journal of Cutaneous Pathology·You Chan KimDongsik Bang
Dec 21, 2010·Advances in Anatomic Pathology·Dmitry V KazakovMichal Michal
Jun 14, 2019·Pediatric Dermatology·Kanchana LeerunyakulSuthinee Rutnin
Apr 12, 2003·Journal of Cutaneous Pathology·Joseph H WillmanJames E Fitzpatrick
Jun 26, 1998·The British Journal of Dermatology·J Y Lee, S C Chao
Sep 15, 2020·Seminars in Diagnostic Pathology·Anastasia M Konstantinova, Dmitry V Kazakov
Oct 27, 2004·Archives of Pathology & Laboratory Medicine·Sujith Prasad Wanniarachchi KumarasingheMarian Priyanthi Kumarasinghe
Aug 20, 2021·The American Journal of Dermatopathology·Pedro ZaballosLuis Requena

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