PMID: 9422325Jan 9, 1998Paper

Clear cell sarcoma of the ileum: the crucial role of cytogenetics for the diagnosis

The American Journal of Surgical Pathology
L R DonnerS Dobin

Abstract

We report a case of clear cell sarcoma that arose in the ileum and metastasized to the liver. The tumor cells did not contain melanin or glycogen; expressed S-100 protein, but not HMB45; and contained possible atypical melanosomes when examined by electron microscopy. They carried a clonal chromosomal rearrangement: 50,XY,t(2;7)(q37;q22),+8,+8,+9,+11, t(12;22)(q13;q12). The diagnosis was greatly facilitated by the cytogenetic analysis. The translocation t(12;22)(q13;q12-13) has been reported as specific for clear cell sarcomas.

References

Dec 1, 1992·The American Journal of Surgical Pathology·D R LucasF H Sim
Jan 1, 1990·American Journal of Clinical Pathology·J A BridgeM Huntrakoon
Apr 1, 1986·Human Pathology·D SawY F Poon
Jan 1, 1985·Ultrastructural Pathology·J D BensonB Mackay
Jan 1, 1983·Virchows Archiv. A, Pathological Anatomy and Histopathology·L G KindblomL Angervall
Jul 1, 1983·The American Journal of Surgical Pathology·E B Chung, F M Enzinger
Oct 15, 1983·Cancer·J J EckardtE H Soule
Oct 1, 1993·The American Journal of Surgical Pathology·S W Weiss, B J Nickoloff

❮ Previous
Next ❯

Citations

Dec 25, 2010·Skeletal Radiology·Weibin ZhangYanBo Zhu
Jul 16, 2005·Virchows Archiv : an International Journal of Pathology·Lorenzo TaminelliLouis Guillou
Oct 13, 2005·Virchows Archiv : an International Journal of Pathology·Wenbin HuangXiaojun Zhou
Dec 4, 2002·Histopathology·P PauwelsP C W Hogendoorn
Jun 10, 2000·Pathology International·T FukudaT Suzuki
May 18, 1999·The American Journal of Surgical Pathology·B P RubinA A Renshaw
Apr 15, 2008·The American Journal of Surgical Pathology·Pamela L LyleWilliam A Robinson
Jul 18, 2015·Clinical Journal of Gastroenterology·Daisuke IshiiShiro Nakano
Nov 8, 2005·International Journal of Surgical Pathology·Nicolaus FriedrichsEva Wardelmann
Apr 7, 2018·Journal of Gastrointestinal Cancer·Gokce AskanOlca Basturk
Jun 27, 2007·Advances in Anatomic Pathology·Richard KirschRobert Riddell
Jul 20, 2007·Virchows Archiv : an International Journal of Pathology·Camilla E CominLuca Messerini
Apr 8, 2009·Pediatric Blood & Cancer·Joanne P LagmayPeter Baker
Nov 29, 2005·APMIS : Acta Pathologica, Microbiologica, Et Immunologica Scandinavica·Girish VenkataramanRasheed Hammadeh
May 21, 2008·Ecological Applications : a Publication of the Ecological Society of America·Nicholas S G WilliamsJohn W Morgan
Mar 7, 2006·Ultrastructural Pathology·Laura GranvilleDolores Lopez-Terrada
Dec 31, 2011·International Journal of Surgical Pathology·Francesco E D'AmicoNicolò Bassi
May 20, 2015·World Journal of Gastroenterology : WJG·Sung Bum KimMi Jin Gu
Apr 14, 2017·World Journal of Gastroenterology : WJG·Hao SuHai-Tao Zhou
Dec 6, 2017·Indian Journal of Surgical Oncology·Surbhi Kansal, Seema Rao
Nov 16, 2011·International Journal of Surgical Pathology·Patrick ShenjereSaumitra S Banerjee
Feb 8, 2020·Indian Journal of Pathology & Microbiology·Mukin Kumar SonaiPrasenjit Das
Aug 26, 2014·International Journal of Surgical Pathology·Gülçin YegenYersu Kapran
Sep 27, 2006·Clinical Cancer Research : an Official Journal of the American Association for Cancer Research·Cristina R AntonescuMarc Ladanyi
Jan 9, 2021·International Journal of Surgical Pathology·Peipei ZhuXianghua Yi
Feb 2, 2021·Journal of Gastrointestinal Cancer·Aditi DamleRoopa Rachel Paulose
Dec 14, 2005·Pathology, Research and Practice·A Agaimy, P H Wünsch

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.