Clindamycin and rifampicin combination therapy for hidradenitis suppurativa

The British Journal of Dermatology
C O Mendonça, C E M Griffiths

Abstract

Hidradenitis suppurativa (HS) is a chronic inflammatory condition affecting apocrine gland-bearing areas of the skin. There is currently no satisfactory treatment. To assess the efficacy of a 10-week course of combination clindamycin 300 mg twice daily and rifampicin 300 mg twice daily in the treatment of HS. Patients who had received combination therapy with clindamycin and rifampicin for HS at one U.K. Dermatology Centre between the years 1998 and 2003 were identified from pharmacy records. Their records were analysed retrospectively. Fourteen patients with HS had received treatment with combination therapy. Eight of these patients achieved remission and a further two achieved remission when minocycline was substituted for clindamycin. Four patients were unable to tolerate therapy. This small retrospective study indicates that combination therapy with clindamycin and rifampicin may be effective for HS. However, there is a need for a placebo-controlled trial.

References

Jan 25, 1986·British Medical Journal·P S MortimerR A Moore
Aug 1, 1988·Journal of the American Academy of Dermatology·D J Hogan, M J Light
Feb 21, 1987·British Medical Journal·B J HarrisonL E Hughes
Jun 1, 1983·International Journal of Dermatology·O J Clemmensen
Jan 1, 1996·Dermatology : International Journal for Clinical and Investigative Dermatology·G B JemecP Wendelboe
Dec 8, 1998·Journal of the American Academy of Dermatology·G B Jemec, P Wendelboe
Sep 25, 1999·Journal of the American Academy of Dermatology·G B Jemec
Mar 22, 2001·Clinical and Experimental Dermatology·R C Brooke, C E Griffiths
Oct 25, 2003·Journal of the American Academy of Dermatology·Benjamin Lebwohl, Allen N Sapadin
Nov 25, 2003·The British Journal of Dermatology·T P SullivanR S Kirsner
Jul 1, 2000·Indian Journal of Dermatology, Venereology and Leprology·A K JaiswalR Verma

❮ Previous
Next ❯

Citations

Dec 19, 2012·Der Hautarzt; Zeitschrift für Dermatologie, Venerologie, und verwandte Gebiete·M MühlstädtC Kunte
May 18, 2010·The Clinical Journal of Pain·Howard S SmithJason Teitelbaum
May 15, 2009·Dermatologic Surgery : Official Publication for American Society for Dermatologic Surgery [et Al.]·Emily TierneyIltefat Hamzavi
Dec 31, 2009·Dermatologic Surgery : Official Publication for American Society for Dermatologic Surgery [et Al.]·Paul G Hazen, Brent P Hazen
Nov 19, 2011·Dermatologic Surgery : Official Publication for American Society for Dermatologic Surgery [et Al.]·Lixia Z Ellis
Oct 26, 2007·Pediatric Dermatology·Joseph LamSheila F Friedlander
Jun 9, 2012·American Journal of Clinical Dermatology·Raed Alhusayen, Neil H Shear
Sep 23, 2014·Paediatric Drugs·Peter Riis Mikkelsen, Gregor B E Jemec
May 19, 2009·Tidsskrift for den Norske lægeforening : tidsskrift for praktisk medicin, ny række·Erlend TolaasKim Alexander Tønseth
Feb 15, 2016·Semergen·F J García-MartínezJ Labandeira-García
Sep 12, 2012·Annales de dermatologie et de vénéréologie·J Revuz
Sep 21, 2011·European Journal of Pharmacology·Maiwand NazaryJurr Boer
Mar 19, 2011·Journal of the American Academy of Dermatology·Dmitri Wall, Brian Kirby
Oct 23, 2010·La Presse médicale·Jean Revuz
Oct 5, 2010·Dermatologic Clinics·F William Danby, Lynette J Margesson
Mar 19, 2009·Journal of the American Academy of Dermatology·Ali AlikhanDaniel B Eisen
Dec 28, 2007·Advances in Dermatology·Robert A LeeJoseph Kist
Dec 15, 2015·Mayo Clinic Proceedings·Carina M WoodruffKieron S Leslie
Jan 30, 2007·Médecine et maladies infectieuses·R ChraïbiB Hassam
Apr 29, 2015·The British Journal of Dermatology·J R Ingram, M McPhee
Aug 18, 2009·Journal of the European Academy of Dermatology and Venereology : JEADV·J Revuz
May 15, 2009·The British Journal of Dermatology·K SartoriusJ Lapins
Oct 13, 2006·The British Journal of Dermatology·A-M ThielenJ-H Saurat
May 11, 2007·Journal of the American Academy of Nurse Practitioners·Amanda C Krbec
Mar 14, 2009·The British Journal of Surgery·M G BuimerJ H G Klinkenbijl
Jan 5, 2011·Photodermatology, Photoimmunology & Photomedicine·Zain U Syed, Iltefat H Hamzavi
Aug 14, 2012·Journal of the European Academy of Dermatology and Venereology : JEADV·R VerdoliniB Mannello
Feb 3, 2015·Journal of the European Academy of Dermatology and Venereology : JEADV·C C ZouboulisG B E Jemec
Mar 5, 2013·Journal of the European Academy of Dermatology and Venereology : JEADV·V BettoliA Virgili
Jun 3, 2009·Clinical and Experimental Dermatology·N Sion-VardyD Benharroch
Dec 1, 2015·Dermatologic Clinics·Vincenzo BettoliAude Nassif
Jul 10, 2013·International Wound Journal·Fabio NicoliValerio Cervelli
Jun 19, 2015·Journal of Plastic, Reconstructive & Aesthetic Surgery : JPRAS·Taku MaedaKikuko Takahashi
Oct 23, 2010·The Journal of Dermatological Treatment·Iben M MillerGregor B E Jemec
Oct 12, 2007·Expert Opinion on Pharmacotherapy·David Guay
Jan 13, 2015·Journal of Pediatric Health Care : Official Publication of National Association of Pediatric Nurse Associates & Practitioners·Molly L Schulman, Hana M Pantuso
Apr 17, 2015·Der Hautarzt; Zeitschrift für Dermatologie, Venerologie, und verwandte Gebiete·J KirschkeF G Bechara
May 22, 2016·The Journal of Investigative Dermatology·Claire HotzSophie Hüe
Oct 1, 2016·Indian Journal of Dermatology·Swetalina PradhanAdarsh Lata Singh
Aug 8, 2015·The International Journal of Lower Extremity Wounds·Valentina DiniMarco Romanelli
Mar 7, 2018·Expert Review of Clinical Immunology·Deborah NegusWilliam Huang
Nov 27, 2010·Dermatology : International Journal for Clinical and Investigative Dermatology·Olivier Join-LambertAude Nassif
Nov 22, 2017·Der Hautarzt; Zeitschrift für Dermatologie, Venerologie, und verwandte Gebiete·R SabatK Wolk

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Dermatology : International Journal for Clinical and Investigative Dermatology
G GenerSylvie Bastuji-Garin
Dermatology : International Journal for Clinical and Investigative Dermatology
Hessel H van der ZeeG B E Jemec
© 2022 Meta ULC. All rights reserved