Clinical activity assessment in inflammatory bowel disease

Digestive Diseases and Sciences
J W Singleton

Abstract

Standardized methods of making and recording clinical observations of patients with inflammatory bowel disease are needed for the conduct of controlled clinical trials and for the application of the results of such trials to clinical practice. A number of attempts to develop such methods have been made since the early 1950s, and such efforts continue at present. A universally accepted and acceptable clinical instrument to measure the disease activity of either Crohn's disease or ulcerative colitis will probably never be achieved. However, if interested clinicians can agree on a basic set of observations and how to make and record them, accurate comparisons of therapeutic outcomes across time and space will become possible. Toward this goal several groups of clinicians are currently working.

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Citations

Jan 1, 1993·Scandinavian Journal of Gastroenterology·J Kjeldsen, O B Schaffalitzky de Muckadell
Jul 1, 1995·Inflammatory Bowel Diseases·H J Hodgson, M Bhatti
Nov 20, 1998·The American Journal of Gastroenterology·M SeoK Oh
Nov 1, 1991·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·C B O'BrienG Salen
Nov 1, 1994·Gut·N MahmudD Kelleher
Feb 13, 2003·Public Health Nutrition·Lois EnglbergerMaureen H Fitzgerald
Aug 4, 2010·Expert Review of Gastroenterology & Hepatology·Rishabh Sehgal, Walter A Koltun
Aug 10, 2018·Intestinal research·Ji Hoon LeeJae Hee Cheon
Dec 1, 1991·Alimentary Pharmacology & Therapeutics·H J Hodgson, M Z Mazlam
Mar 1, 1997·Baillière's Clinical Gastroenterology·K LeiperJ M Rhodes

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