Clinical and angiographic predictors of short- and long-term ischemic events in acute coronary syndromes: results from the Acute Catheterization and Urgent Intervention Triage strategY (ACUITY) trial

Circulation. Cardiovascular Interventions
Alexandra J LanskyGregg W Stone

Abstract

Contemporary adjunctive pharmacology and revascularization strategies have improved the prognosis of patients with acute coronary syndromes (ACSs). We sought to identify the clinical and angiographic predictors of cardiac ischemic events in patients with ACSs treated with an early invasive strategy. Multivariable logistic regression was used to analyze the relation between baseline characteristics and 30-day and 1-year composite ischemia (death, myocardial infarction, or unplanned revascularization) among the 6921 ACS patients included in the prespecified angiographic substudy of the Acute Catheterization and Urgent Intervention Triage strategY (ACUITY) trial. Of the 6921 patients, 3826 (55.3%) were treated with percutaneous coronary intervention, 755 (10.9%) with coronary artery bypass grafting, and 2340 (33.8%) with medical therapy. Composite ischemia occurred in 595 (8.6%) patients at 30 days and in 1153 (17.4%) at 1 year. Renal insufficiency, biomarker elevation, ST-segment deviation, nonuse of aspirin or thienopyridine, insulin-treated diabetes, older age, baseline lower hemoglobin value, history of percutaneous coronary intervention, and current smoking were independently associated with 30-day or 1-year ischemic events. ...Continue Reading

References

May 1, 1985·Journal of the American College of Cardiology·R M CaliffG S Wagner
Mar 15, 1996·Journal of the American College of Cardiology·E M TuzcuS E Nissen
Aug 11, 2000·JAMA : the Journal of the American Medical Association·E M AntmanE Braunwald
Jun 23, 2001·The New England Journal of Medicine·C P CannonUNKNOWN TACTICS (Treat Angina with Aggrastat and Determine Cost of Therapy with an Invasive or Conservative Strategy)--Thrombolysis
Dec 31, 2002·European Heart Journal·Michel E BertrandUNKNOWN Task Force on the Management of Acute Coronary Syndromes of the European Society of Cardiology
Jun 10, 2004·JAMA : the Journal of the American Medical Association·Kim A EagleUNKNOWN GRACE Investigators
Feb 8, 2005·The American Journal of Cardiology·Hideo TakebayashiJeffrey W Moses
May 10, 2005·The American Journal of Cardiology·Nico R MolletPim J de Feyter
Sep 5, 2006·Journal of the American College of Cardiology·Cynthia M WesterhoutUNKNOWN GUSTO-IV ACS Trial Investigators
Nov 25, 2006·The New England Journal of Medicine·Gregg W StoneUNKNOWN ACUITY Investigators
Jan 24, 2007·American Heart Journal·Jose de Ribamar CostaMartin B Leon
Dec 7, 2007·JAMA : the Journal of the American Medical Association·Gregg W StoneUNKNOWN ACUITY Investigators

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Citations

Aug 25, 2012·EuroIntervention : Journal of EuroPCR in Collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology·Amit SegevUNKNOWN ACSIS and ACSIS-PCI 2010 investigators
Feb 22, 2011·The International Journal of Cardiovascular Imaging·Vivian G Ng, Alexandra J Lansky
Oct 30, 2016·European Heart Journal·Nicolas BettingerPhilippe Généreux
Nov 24, 2011·Catheterization and Cardiovascular Interventions : Official Journal of the Society for Cardiac Angiography & Interventions·Kenneth TandjungClemens von Birgelen
Jan 10, 2014·Catheterization and Cardiovascular Interventions : Official Journal of the Society for Cardiac Angiography & Interventions·Barış GüngörOsman Bolca
Nov 28, 2013·Catheterization and Cardiovascular Interventions : Official Journal of the Society for Cardiac Angiography & Interventions·Fabio AngeliClaudio Cavallini
Sep 10, 2013·Journal of cardiology·Mehmet Akif CakarHuseyin Gunduz
Sep 13, 2014·Journal of the American College of Cardiology·Ron Waksman, Michael J Lipinski
May 9, 2012·The International Journal of Lower Extremity Wounds·Thoetphum BenyakornKittipan Rerkasem
Dec 16, 2010·Circulation. Cardiovascular Interventions·Alexandra J Lansky, Gregg W Stone
Jan 20, 2016·Journal of Cardiovascular Medicine·Marco MoltrasioGiancarlo Marenzi
Jul 10, 2012·Journal of Cardiovascular Medicine·Nevio TaglieriAntonio Marzocchi
Mar 5, 2021·Catheterization and Cardiovascular Interventions : Official Journal of the Society for Cardiac Angiography & Interventions·M Bilal IqbalUNKNOWN British Columbia Cardiac Registry Investigators
Jul 11, 2020·JACC. Cardiovascular Interventions·Kevin R BaineyRobert C Welsh

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