Clinical and Antimicrobial Efficacy of a Silver Foam Dressing With Silicone Adhesive in Diabetic Foot Ulcers With Mild Infection

The International Journal of Lower Extremity Wounds
José Luis Lázaro-MartínezE García-Morales

Abstract

The use of an antimicrobial dressing instead of a non-antimicrobial dressing may increase the number of diabetic foot ulcers healed over a medium-term follow-up period. The study aim was to evaluate the clinical and microbiological efficacy of a silver foam dressing in the management of diabetic foot ulcers. We conducted a single-center, prospective, open, noncontrolled study involving 21 outpatients with diabetic foot ulcers with mild infection. All patients received standard of care for their wounds and a silver foam dressing with silicone adhesive was applied twice per week for wound management during a 6-week treatment period. Soft tissue punch biopsies were taken every second week for qualitative and quantitative microbiological analysis. Wounds were assessed at patient admission, and wound bed tissue was evaluated for presence, quality, and consistency of granulation tissue. Clinical evaluation revealed improvements in wound conditions as a result of treatment with the silver dressing. Wollina wound scores improved significantly, from a mean score of 3.9 ± 1.6 points at inclusion to 6.1 ± 1.3 points at the end of the study (n = 19, P < .001). Treatment with the silver dressing resulted in significant decreases in the biob...Continue Reading

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Citations

Feb 11, 2020·The International Journal of Lower Extremity Wounds·Nikolaos PapanasSoultana Kyroglou
Sep 14, 2019·The International Journal of Lower Extremity Wounds·Nikolaos PapanasKittipan Rerkasem
Apr 29, 2021·The International Journal of Lower Extremity Wounds·Raul Juan Molines-BarrosoJosé Luis Lázaro-Martínez
May 1, 2021·Journal of Clinical Medicine·Yu-Chi WangYur-Ren Kuo
Jun 3, 2021·Journal of Clinical Medicine·Gianmarco Matta-GutiérrezJosé Luis Lázaro-Martínez
Jul 29, 2021·Journal of Applied Microbiology·Andreea-Gabriela NedeleaSarah E Maddocks

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