Clinical and arrhythmic outcomes after implantation of a defibrillator for primary prevention of sudden death in patients with post-myocardial infarction cardiomyopathy: The Survey to Evaluate Arrhythmia Rate in High-risk MI patients (SEARCH-MI).

Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups on Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology
Massimo SantiniGiuseppe Boriani

Abstract

To evaluate clinical and arrhythmic outcomes in post-infarction cardiomyopathy patients implanted with a defibrillator (ICD) for primary prevention of sudden death. The SEARCH-MI registry is a European multi-centre, prospective, observational study enrolling patients after myocardial infarction, chronic left ventricular dysfunction and an ICD implanted for primary prevention of sudden death. Data on 556 patients with at least one recorded follow-up are presented. Survey to Evaluate Arrhythmia Rate in High-risk MI (SEARCH-MI) patients were sicker than those enrolled in MADIT-II with higher New York Heart Association class and left bundle branch block. Total mortality was 10.4%. Close to one-third (30%) of patients experienced episodes of sustained ventricular arrhythmia. One-quarter (23%) received at least one appropriate therapy and 10% inappropriate therapy. Gender (25% males vs. 5% females, P = 0.0009) and history of non-sustained ventricular tachycardia (24% with vs. 18% without P = 0.037) were predictive of appropriate ventricular therapy. SEARCH-MI represents the current clinical management of post-MI patients with left ventricular dysfunction indicated to defibrillator implant for primary prevention. European routine clin...Continue Reading

References

Nov 24, 1983·The New England Journal of Medicine·J N RuskinE Kelly
May 1, 1984·The American Journal of Cardiology·A E BuxtonM E Josephson
Aug 15, 1998·American Heart Journal·W B KannelJ Cobb
Mar 22, 2002·The New England Journal of Medicine·Arthur J MossUNKNOWN Multicenter Automatic Defibrillator Implantation Trial II Investigators
Dec 12, 2002·Journal of Cardiovascular Electrophysiology·Gabriel GregoratosUNKNOWN American College of Cardiology/American Heart Association Task Force on Practice Guidelines American College of Cardiology/A
May 27, 2003·Cardiac Electrophysiology Review·Vidal Essebag, Mark J Eisenberg
Mar 10, 2004·Circulation·Eric N Prystowsky
Apr 20, 2004·Journal of the American College of Cardiology·Henry GreenbergUNKNOWN MADIT-II Investigators
May 21, 2004·The New England Journal of Medicine·Michael R BristowUNKNOWN Comparison of Medical Therapy, Pacing, and Defibrillation in Heart Failure (COMPANION) Investigators
Dec 8, 2004·Circulation·Arthur J MossUNKNOWN Multicenter Automatic Defibrillator Implantation Trial-II (MADIT-II) Research Group
Jan 22, 2005·The New England Journal of Medicine·Gust H BardyUNKNOWN Sudden Cardiac Death in Heart Failure Trial (SCD-HeFT) Investigators
Mar 9, 2005·The New England Journal of Medicine·John G F ClelandUNKNOWN Cardiac Resynchronization-Heart Failure (CARE-HF) Study Investigators
Apr 20, 2005·Annals of Internal Medicine·Sana M Al-KhatibRobert M Califf
Jul 19, 2005·Journal of the American College of Cardiology·Alfred E BuxtonUNKNOWN PainFREE Rx II Investigators
Jan 13, 2006·Journal of Cardiovascular Electrophysiology·Wojciech ZarebaUNKNOWN MADIT II Investigators
Jun 2, 2007·American Heart Journal·Sana M Al-KhatibUNKNOWN Expert panel participating in a Duke's Center for the Prevention of Sudden Cardiac Death conference
Jun 2, 2007·American Heart Journal·Gillian D SandersUNKNOWN Expert panel participating in a Duke Center for the Prevention of Sudden Cardiac Death-sponsored conference
Oct 4, 2007·JAMA : the Journal of the American Medical Association·Lesley H CurtisKevin A Schulman
May 3, 2008·Heart Rhythm : the Official Journal of the Heart Rhythm Society·Peter W GroeneveldFeifei Yang
Jun 12, 2008·JAMA : the Journal of the American Medical Association·Norman C WangUNKNOWN Efficacy of Vasopressin Antagonism in Heart Failure Outcome Study With Tolvaptan (EVEREST) Investigators

❮ Previous
Next ❯

Citations

Mar 13, 2009·Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups on Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology·Suzanne Valk, Luc Jordaens
Jul 29, 2010·Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups on Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology·A John Camm, Seah Nisam
Dec 7, 2010·Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups on Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology·Faisal F SyedJohnson Francis
Jun 30, 2011·Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups on Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology·Beat SchaerDominic A Theuns
Jun 2, 2012·Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups on Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology·Lara Dabiri Abkenari, Luc Jordaens
May 2, 2012·Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups on Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology·Antoine LeenhardtUNKNOWN OPERA Registry Investigators
Oct 31, 2012·World Journal of Cardiology·Aimé BonnyGuy Fontaine
Jul 25, 2012·Cardiology in the Young·Georgia Sarquella-BrugadaRamon Brugada
Aug 21, 2015·Pacing and Clinical Electrophysiology : PACE·Lidia R BonsDominic A M J Theuns
Jul 21, 2011·Netherlands Heart Journal : Monthly Journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation·T SmithL Jordaens

❮ Previous
Next ❯

Software Mentioned

MI
SEARCH
MADIT
MUSTT
II

Related Concepts

Related Feeds

Cardiomyopathy

Cardiomyopathy is a disease of the heart muscle, that can lead to muscular or electrical dysfunction of the heart. It is often an irreversible disease that is associated with a poor prognosis. There are different causes and classifications of cardiomyopathies. Here are the latest discoveries pertaining to this disease.

Arrhythmia

Arrhythmias are abnormalities in heart rhythms, which can be either too fast or too slow. They can result from abnormalities of the initiation of an impulse or impulse conduction or a combination of both. Here is the latest research on arrhythmias.

Atrial Fibrillation

Atrial fibrillation is a common arrhythmia that is associated with substantial morbidity and mortality, particularly due to stroke and thromboembolism. Here is the latest research.

Related Papers

The New England Journal of Medicine
Arthur J MossMulticenter Automatic Defibrillator Implantation Trial II Investigators
Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups on Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology
Alessandro ProclemerMichele Brignole
Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups on Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology
Bela MerkelyChristian Wolpert
© 2021 Meta ULC. All rights reserved