Clinical and bacteriological features of six cases with intracranial abscess in childhood

Kansenshōgaku zasshi. The Journal of the Japanese Association for Infectious Diseases
Tadashi Hoshino, Akira Nakamura

Abstract

From October 1988 to March 2001, 5 patients with 6 episodes of intracranial abscesses were admitted to Chiba-Children's Hospital. Average age when they were admitted was 10 years and 1 month. Initial clinical symptoms were fever in 5 cases, and headache in 1 case. It took 21 days from the appearance of the initial symptoms to diagnose the intracranial abscess. Four out of 5 patients had underlying diseases that were prone to cause intracranial abscess. Two patients of these were cyanotic congenital heart diseases (tetralogy of Fallot and asplenic heart), and the other 2 were sinusitis. Computed tomography revealed that brain abscess was found in 5 cases, and subdural empyema in 1 case. There were 3 single and multiple abscesses each. The most common lesion was the temporal lobe. Eight bacterial strains were isolated from 5 cases. Five were streptococci (3 were Streptococcus milleri group, other 2 were Streptococcus oralis and microaerophilic Streptococcus) and 3 were anaerobes (Prevotella loescheii, Prevotella bivia and Fusobacterium nucleatum). Antimicrobial therapy was started with panipenem-betamiprone in 3 cases, imipenem-cilastatin, ceftriaxone, and ampicillin in the other cases resre ctinely. Duration of therapy ranged fr...Continue Reading

Citations

Mar 26, 2014·BMC Infectious Diseases·Mansoor MehmoodFaisal A Khasawneh
Jan 24, 2014·Journal of Clinical Microbiology·Alessandro Di Marco BerardinoTeresa Spanu
Oct 3, 2017·The Journal of Craniofacial Surgery·Tadahide NoguchiYoshiyuki Mori

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